methyl 2-hydroxytricyclo[3.3.1.1~3,7~]decane-1-carboxylate

Base Information

• Chemical Name: methyl 2-hydroxytricyclo[3.3.1.1~3,7~]decane-1-carboxylate
• CAS No.: 41171-74-8
• Molecular Formula: C12H18O3
• Molecular Weight: 210.2695
• Hs Code.: 2918199090
• Mol file: 41171-74-8.mol

Synonyms:Methyl 2-hydroxy-1-adamantanecarboxylate;Tricyclo[3.3.1.1(3,7)]decane-2-ol-1-carboxylic acid,methyl ester;Methyl-2-adamantanol-1-carboxylat;1-Carbomethoxyadamantan-2-ol;

Chemical Property of methyl 2-hydroxytricyclo[3.3.1.1~3,7~]decane-1-carboxylate

Chemical Property:

• Vapor Pressure: 9.23E-05mmHg at 25°C
• Boiling Point: 303°Cat760mmHg
• PKA: 14.18±0.40(Predicted)
• Flash Point: 124.3°C
• PSA: 46.53000
• Density: 1.245g/cm³
• LogP: 1.34660

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methyl 2-hydroxytricyclo[3.3.1.1~3,7~]decane-1-carboxylate

There total 4 articles about methyl 2-hydroxytricyclo[3.3.1.1~3,7~]decane-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-hydroxy-1-adamantanomethanol (59182-38-6) → Methyl-2-adamantanol-1-carboxylat (41171-74-8)

Guidance literature:

Multi-step reaction with 2 steps

1: CrO₃, H₂SO₄

2: NaBH₄

With chromium(VI) oxide; sodium tetrahydroborate; sulfuric acid;

DOI:10.1021/ja00433a041

Reference yield:

methanol (67-56-1) + 2-oxoadamantane-1-carboxylic acid (40556-86-3) → Methyl-2-adamantanol-1-carboxylat (41171-74-8)

Guidance literature:

With sodium tetrahydroborate;

DOI:10.1021/ja00433a041

Reference yield:

2-oxoadamantane-1-carboxylic acid (40556-86-3) → Methyl-2-adamantanol-1-carboxylat (41171-74-8)

Guidance literature:

Multi-step reaction with 2 steps

1: NaBH₄

With sodium tetrahydroborate;

DOI:10.1021/jo00960a001

upstream raw materials:

diazomethane

1-carboxy-2-adamantanol

methanol

2-oxoadamantane-1-carboxylic acid