Piperidine-4-carboxamide hydrochloride

Base Information

Chemical Name:Piperidine-4-carboxamide hydrochloride
CAS No.:39674-99-2
Molecular Formula:C6H12N2O
Molecular Weight:164.635
Hs Code.:
European Community (EC) Number:848-512-0
DSSTox Substance ID:DTXSID00591347
NSC Number:203097
Mol file:39674-99-2.mol

Synonyms:piperidine-4-carboxamide hydrochloride;39674-99-2;4-PIPERIDINECARBOXAMIDE HYDROCHLORIDE;piperidine-4-carboxamide;hydrochloride;4 - piperidinyl-carboxamide hydrochloride;MFCD11615743;4-Piperidinylcarboxamide HCl;SCHEMBL2674808;DTXSID00591347;PIPERIDINE-4-CARBOXAMIDE HCL;piperidine-4-carboxamidehydrochloride;NSC203097;AKOS015847505;NSC-203097;SB41664;DS-15909;SY112441;DB-159835;CS-0149954;C75011;EN300-1265946;Piperidine-4-carboxamide--hydrogen chloride (1/1);F8881-4365;Z1450533743

Suppliers and Price of Piperidine-4-carboxamide hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of Piperidine-4-carboxamide hydrochloride

Chemical Property:

Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:164.0716407
Heavy Atom Count:10
Complexity:108

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCCC1C(=O)N.Cl

Technology Process of Piperidine-4-carboxamide hydrochloride

There total 4 articles about Piperidine-4-carboxamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1453-82-3
isonicotinamide

: 39674-99-2
4-piperidine-carboxamide hydrochloride

Guidance literature:: With 1,1,2-trichloroethane; palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 10h; under 2585.81 Torr;
DOI:10.1016/j.tet.2009.08.011

Reference yield: 97.0%

: 91419-48-6
4-carbamoyl-piperidine-1-carboxylic acid tert-butyl ester

: 39674-99-2
4-piperidine-carboxamide hydrochloride

Guidance literature:: With hydrogenchloride; In dichloromethane; ethyl acetate; at 20 ℃; for 0.5h; Inert atmosphere;

Reference yield:

: 124443-68-1
1-tert-Butyl 4-methyl piperidine-1,4-dicarboxylate

: 39674-99-2
4-piperidine-carboxamide hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: lithium hydroxide monohydrate / tetrahydrofuran; water / 1 h / 45 °C

2: 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; ammonium chloride / dichloromethane / 10 h / 0 - 20 °C

3: hydrogenchloride / dichloromethane; ethyl acetate / 0.5 h / 20 °C

With hydrogenchloride; 1-hydroxy-7-aza-benzotriazole; lithium hydroxide monohydrate; ammonium chloride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; water; ethyl acetate;