N-[9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-oxo-7H-purin-6-yl]acetamide

Base Information

Chemical Name:N-[9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-oxo-7H-purin-6-yl]acetamide
CAS No.:3868-35-7
Molecular Formula:C₁₂H₁₅N₅O₆
Molecular Weight:325.281
Hs Code.:
NSC Number:91778
DSSTox Substance ID:DTXSID50293728
Mol file:3868-35-7.mol

Synonyms:3868-35-7;NSC91778;N-[9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-oxo-7H-purin-6-yl]acetamide;DTXSID50293728;NSC-91778

Suppliers and Price of N-[9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-oxo-7H-purin-6-yl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N-[9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-oxo-7H-purin-6-yl]acetamide

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.733g/cm³
XLogP3:-2.6
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:3
Exact Mass:325.10223322
Heavy Atom Count:23
Complexity:493

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=C2C(=NC=N1)N(C(=O)N2)C3C(C(C(O3)CO)O)O

Technology Process of N-[9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-oxo-7H-purin-6-yl]acetamide

There total 5 articles about N-[9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-oxo-7H-purin-6-yl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 29851-55-6
N-acetyl-8-oxo-7,8-dihydroadenosine-,2’,3’,5’-triacetate

: 3868-35-7
6-N-acetyl-8-oxoadenosine

Guidance literature:: With pyridine amine; at 20 ℃; for 6h;
DOI:10.1016/S0040-4039(00)00926-6

Reference yield:

: 2946-39-6
8-bromoadenosine

: 3868-35-7
6-N-acetyl-8-oxoadenosine

Guidance literature:: Multi-step reaction with 3 steps

2: NaOAc; AcOH / 3 h / 120 °C

3: NH₃*pyridine / 6 h / 20 °C

With pyridine amine; sodium acetate; acetic acid; 1: Hydrolysis / 2: Acetylation / 3: Deacetylation;
DOI:10.1016/S0040-4039(00)00926-6

Reference yield:

: 19325-87-2,19325-89-4,29851-57-8
8-oxoadenosine

: 3868-35-7
6-N-acetyl-8-oxoadenosine

Guidance literature:: Multi-step reaction with 2 steps

1: NaOAc; AcOH / 3 h / 120 °C

2: NH₃*pyridine / 6 h / 20 °C

With pyridine amine; sodium acetate; acetic acid; 1: Acetylation / 2: Deacetylation;
DOI:10.1016/S0040-4039(00)00926-6