10-(4-Methoxyphenyl)-3,4,9,10-tetrahydropyrrolo(3,4-b)(1,5)benzodiazepin-1(2H)-one

Base Information

Chemical Name:10-(4-Methoxyphenyl)-3,4,9,10-tetrahydropyrrolo(3,4-b)(1,5)benzodiazepin-1(2H)-one
CAS No.:137987-37-2
Molecular Formula:C18H17N3O2
Molecular Weight:307.3465
Hs Code.:
DSSTox Substance ID:DTXSID60929960
Nikkaji Number:J445.491J
Mol file:137987-37-2.mol

Synonyms:137987-37-2;10-(4-Methoxyphenyl)-3,4,9,10-tetrahydropyrrolo(3,4-b)(1,5)benzodiazepin-1(2H)-one;Pyrrolo(3,4-b)(1,5)benzodiazepin-1(2H)-one, 3,4,9,10-tetrahydro-10-(4-methoxyphenyl)-, hemihydrate;4-(4-methoxyphenyl)-2,4,5,10-tetrahydro-1H-pyrrolo[3,4-c][1,5]benzodiazepin-3-one;10-(4-methoxyphenyl)-3,4,9,10-tetrahydropyrrolo[3,4-b][1,5]benzodiazepin-1(2H)-one;Cambridge id 5477007;Oprea1_318020;DTXSID60929960;DHTAOKLCLVWLJI-UHFFFAOYSA-N;CCG-16875;AKOS030490755;C18H17N3O2.1/2H2O;LS-139288;C18-H17-N3-O2.1/2H2-O;AB00086460-01;AH-262/34398028;SR-01000437682;SR-01000437682-1;10-(4-Methoxyphenyl)-3,4,9,10-tetrahydropyrrolo[3,4-b][1,5]benzodiazepin-1-ol;3,4,9,10-Tetrahydro-10-(4-methoxyphenyl)pyrrolo[3,4-b][1,5]benzodiazepin-1(2H)-one

Suppliers and Price of 10-(4-Methoxyphenyl)-3,4,9,10-tetrahydropyrrolo(3,4-b)(1,5)benzodiazepin-1(2H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 10-(4-Methoxyphenyl)-3,4,9,10-tetrahydropyrrolo(3,4-b)(1,5)benzodiazepin-1(2H)-one

Chemical Property:

Vapor Pressure:6.24E-14mmHg at 25°C
Boiling Point:590.8°C at 760 mmHg
Flash Point:311.1°C
PSA：65.88000
Density:1.33g/cm³
LogP:3.20970
XLogP3:2.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:307.132076794
Heavy Atom Count:23
Complexity:497

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2C3=C(CNC3=O)NC4=CC=CC=C4N2

Technology Process of 10-(4-Methoxyphenyl)-3,4,9,10-tetrahydropyrrolo(3,4-b)(1,5)benzodiazepin-1(2H)-one

There total 2 articles about 10-(4-Methoxyphenyl)-3,4,9,10-tetrahydropyrrolo(3,4-b)(1,5)benzodiazepin-1(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 123-11-5
4-methoxy-benzaldehyde

: 137987-35-0
4-(2-aminophenyl)aminopyrroline-2-one

: 137987-37-2
10-(4-Methoxy-phenyl)-3,4,9,10-tetrahydro-2H-benzo[b]pyrrolo[3,4-e][1,4]diazepin-1-one

Guidance literature:: With acetic acid; In ethanol;
DOI:10.1007/BF00767253

Reference yield:

: 95-54-5
1,2-diamino-benzene

: 137987-37-2
10-(4-Methoxy-phenyl)-3,4,9,10-tetrahydro-2H-benzo[b]pyrrolo[3,4-e][1,4]diazepin-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / methanol / 1 h / Heating

2: 95 percent / AcOH / ethanol

With acetic acid; In methanol; ethanol;
DOI:10.1007/BF00767253