2-(5-Methyl-2-furyl)aniline hydrochloride

Base Information

• Chemical Name: 2-(5-Methyl-2-furyl)aniline hydrochloride
• CAS No.: 5663-85-4
• Molecular Formula: C11H12ClNO
• Molecular Weight: 202.296
• DSSTox Substance ID: DTXSID70386323
• Mol file: 5663-85-4.mol

Synonyms:2-(5-Methyl-2-furyl)aniline hydrochloride;329187-42-0;2-(5-methylfuran-2-yl)aniline hydrochloride;2-(5-Methyl-2-furyl)aniline, HCl;5663-85-4;2-(5-methylfuran-2-yl)aniline;hydrochloride;BIM-0027356.P001;Cambridge id 5663854;DTXSID70386323;AKOS026675610;PS-8020;2-(5-Methylfur-2-yl)aniline hydrochloride;2-(5-methylfuran-2-yl)anilinehydrochloride;CS-0323557;J-018934

Chemical Property of 2-(5-Methyl-2-furyl)aniline hydrochloride

Chemical Property:

• Vapor Pressure: 0.00461mmHg at 25°C
• Boiling Point: 277.1°Cat760mmHg
• Flash Point: 121.4°C
• Density: g/cm³
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 209.0607417
• Heavy Atom Count: 14
• Complexity: 172

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(O1)C2=CC=CC=C2N.Cl

Technology Process of 2-(5-Methyl-2-furyl)aniline hydrochloride

There total 17 articles about 2-(5-Methyl-2-furyl)aniline hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

hexanal (66-25-1) + acetophenone (98-86-2) → (E)-1-phenyl-2-octen-1-one (5663-85-4)

Guidance literature:

acetophenone; With sodium hydroxide; In ethanol; water; at 0 ℃; for 0.0833333h;

hexanal; In ethanol; water; for 0.0833333h;

DOI:10.1002/anie.201811471

Reference yield: 86.0%

n-octanophenone (1674-37-9) → (E)-1-phenyl-2-octen-1-one (5663-85-4)

Guidance literature:

With toluene-4-sulfonic acid; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In fluorobenzene; dimethyl sulfoxide; at 85 ℃; for 8h;

DOI:10.1021/ja012127+

Reference yield: 83.0%

(2E)-1-phenyloct-2-en-1-ol (181229-27-6) → (E)-1-phenyl-2-octen-1-one (5663-85-4)

Guidance literature:

With manganese(IV) oxide; In tetrahydrofuran; at 20 ℃; for 2h;

DOI:10.1016/j.tetlet.2013.10.085

upstream raw materials:

acetophenone N-ethoxycarbonylhydrazone

hexanal

hept-1-en-t-yl-trimethyl-silane

benzoyl chloride