2-(4-Dimethylvinylphenyl)propionic acid

Base Information

Chemical Name:2-(4-Dimethylvinylphenyl)propionic acid
CAS No.:75625-99-9
Deprecated CAS:107672-15-1
Molecular Formula:C13H16 O2
Molecular Weight:204.269
Hs Code.:
DSSTox Substance ID:DTXSID40910472
Nikkaji Number:J325.960I
ChEMBL ID:CHEMBL230013
Mol file:75625-99-9.mol

Synonyms:2-(4-dimethylvinylphenyl)propionic acid;Gx 258;Gx-258

Suppliers and Price of 2-(4-Dimethylvinylphenyl)propionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-[4-(2-Methylpropenyl)phenyl]propionicAcid
250mg
$ 545.00

TRC
2-[4-(2-Methylpropenyl)phenyl]propionicAcid
500mg
$ 1040.00

Medical Isotopes, Inc.
2-[4-(2-Methyl-propenyl)phenyl]propionicAcid
100 mg
$ 860.00

American Custom Chemicals Corporation
2-[4-(2-METHYL-PROPENYL)PHENYL]PROPIONIC ACID 95.00%
1G
$ 1593.90

American Custom Chemicals Corporation
2-[4-(2-METHYL-PROPENYL)PHENYL]PROPIONIC ACID 95.00%
100MG
$ 704.55

Total 9 raw suppliers

Chemical Property of 2-(4-Dimethylvinylphenyl)propionic acid

Chemical Property:

Vapor Pressure:5.32E-05mmHg at 25°C
Melting Point:50-52 °C(Solv: hexane (110-54-3))
Boiling Point:333.7°C at 760 mmHg
PKA:4.44±0.10(Predicted)
Flash Point:230.7°C
PSA：37.30000
Density:1.067g/cm³
LogP:3.29790
Storage Temp.:-20°C Freezer, Under inert atmosphere
Solubility.:Chloroform (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:204.115029749
Heavy Atom Count:15
Complexity:243

Purity/Quality:

> 95% ^*data from raw suppliers

2-[4-(2-Methylpropenyl)phenyl]propionicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=C(C=C1)C=C(C)C)C(=O)O
Uses 2-[4-(2-Methylpropenyl)phenyl]propionic Acid is a byproduct of Ibuprofen (I140000(P)), which is an anti-inflammatory drug.

Technology Process of 2-(4-Dimethylvinylphenyl)propionic acid

There total 12 articles about 2-(4-Dimethylvinylphenyl)propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 77601-60-6
ethyl 2-<(4-(2-methyl-1-propenyl)phenyl)>propionate

: 75625-99-9,107672-15-1
2-(4'-<2-methyl-1-propenyl>phenyl)propanoic acid

Guidance literature:: With sodium hydroxide; In ethanol; water; for 6h; Ambient temperature;
DOI:10.1248/cpb.34.4653

Reference yield: 85.0%

: methyl 2-{4-[(2-methylprop-1-enyl)phenyl]}propanoate

: 75625-99-9,107672-15-1
2-(4'-<2-methyl-1-propenyl>phenyl)propanoic acid

Guidance literature:: With potassium hydroxide; In ethanol; at 20 ℃; for 4h;
DOI:10.1021/jm061469t

Reference yield: 71.0%

: C₂₁H₁₇O₂S₂⁽¹⁺⁾*CF₃O₃S^(1-)

: 126689-00-7
2-methyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-propene

: 75625-99-9,107672-15-1
2-(4'-<2-methyl-1-propenyl>phenyl)propanoic acid

Guidance literature:: With bis(tri-t-butylphosphine)palladium⁽⁰⁾; sodium hydrogencarbonate; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 12h; Inert atmosphere; Schlenk technique;
DOI:10.1039/d0cc00641f