4-Butyl-2-phenyl-2-propoxymorpholine hydrochloride

Base Information

• Chemical Name: 4-Butyl-2-phenyl-2-propoxymorpholine hydrochloride
• CAS No.: 126806-94-8
• Molecular Formula: C₁₇H₂₇NO₂*ClH
• Molecular Weight: 313.868
• DSSTox Substance ID: DTXSID80925702
• Mol file: 126806-94-8.mol

Synonyms:4-Butyl-2-phenyl-2-propoxymorpholine hydrochloride;Morpholine, 4-butyl-2-phenyl-2-propoxy-, hydrochloride;126806-94-8;DTXSID80925702;LS-92495;4-Butyl-2-phenyl-2-propoxymorpholine--hydrogen chloride (1/1)

Chemical Property of 4-Butyl-2-phenyl-2-propoxymorpholine hydrochloride

Chemical Property:

• Vapor Pressure: 1.2E-05mmHg at 25°C
• Boiling Point: 369.2°Cat760mmHg
• Flash Point: 110.7°C
• Density: g/cm³
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 313.1808568
• Heavy Atom Count: 21
• Complexity: 266

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCN1CCOC(C1)(C2=CC=CC=C2)OCCC.Cl

Technology Process of 4-Butyl-2-phenyl-2-propoxymorpholine hydrochloride

There total 3 articles about 4-Butyl-2-phenyl-2-propoxymorpholine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

propan-1-ol (71-23-8) + 4-Butyl-2-phenyl-morpholin-2-ol; hydrochloride (126806-92-6) → 4-Butyl-2-phenyl-2-propoxy-morpholine; hydrochloride (126806-94-8)

Guidance literature:

With acid; Heating;

DOI:10.1002/ardp.19903230114

Reference yield:

2-butylamino-ethanol (111-75-1) → 4-Butyl-2-phenyl-2-propoxy-morpholine; hydrochloride (126806-94-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 68 percent / diethyl ether

2: 77 percent / acid / Heating

With acid; In diethyl ether;

DOI:10.1002/ardp.19903230114

Reference yield:

α-bromoacetophenone (70-11-1) → 4-Butyl-2-phenyl-2-propoxy-morpholine; hydrochloride (126806-94-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 68 percent / diethyl ether

2: 77 percent / acid / Heating

With acid; In diethyl ether;

DOI:10.1002/ardp.19903230114

upstream raw materials:

propan-1-ol

4-Butyl-2-phenyl-morpholin-2-ol; hydrochloride

2-butylamino-ethanol

α-bromoacetophenone