N-[2-(diethylamino)ethyl]-N-ethylbenzamide

Base Information

• Chemical Name: N-[2-(diethylamino)ethyl]-N-ethylbenzamide
• CAS No.: 103562-84-1
• Molecular Formula: C15H24 N2 O
• Molecular Weight: 248.368
• Mol file: 103562-84-1.mol

Synonyms:

Chemical Property of N-[2-(diethylamino)ethyl]-N-ethylbenzamide

Chemical Property:

• Vapor Pressure: 1.49E-05mmHg at 25°C
• Boiling Point: 366.2°C at 760 mmHg
• Flash Point: 144°C
• Density: 0.989g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-[2-(diethylamino)ethyl]-N-ethylbenzamide

There total 1 articles about N-[2-(diethylamino)ethyl]-N-ethylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

N,N,N'-triethylethanediamine (105-04-4) + benzoyl chloride (98-88-4) → N-<2-(diethylamino)ethyl>-N-ethylbenzamide (103562-84-1)

Guidance literature:

With sodium hydroxide; In dichloromethane; for 5h; Ambient temperature;

DOI:10.1021/jo00369a002

Reference yield:

benzaldehyde (100-52-7) + N-<2-(diethylamino)ethyl>-N-ethylbenzamide (103562-84-1) → 3-phenylphthalide (5398-11-8)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1021/jo00369a002

Reference yield:

N-<2-(diethylamino)ethyl>-N-ethylbenzamide (103562-84-1) → 2-Fluoranthen-3-ylmethyl-benzoic acid (111189-48-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) sec-butyllithium, TMEDA / 1.) THF, 1 h, 2.) THF, RT, overnight

2: 74 percent / H₂ / 10percent palladium/charcoal / ethyl acetate / 24 h / 2585.7 Torr / Ambient temperature

With N,N,N,N,-tetramethylethylenediamine; hydrogen; sec.-butyllithium; palladium on activated charcoal; In ethyl acetate;

DOI:10.1021/jo00235a005

upstream raw materials:

N,N,N'-triethylethanediamine

benzoyl chloride

Downstream raw materials:

3-Fluoranthen-3-yl-3H-isobenzofuran-1-one

3-phenylphthalide

3-hydroxy-1(3H)-isobenzofuranone

o-methyl-N-<2-(diethylamino)ethyl>-N-ethylbenzamide