1-Phenethylpiperidin-4-ol

Base Information

Chemical Name:1-Phenethylpiperidin-4-ol
CAS No.:3518-76-1
Molecular Formula:C13H19 N O
Molecular Weight:205.3
Hs Code.:2933399090
European Community (EC) Number:222-527-7
UNII:U62RHL2Y72
DSSTox Substance ID:DTXSID90188669
Nikkaji Number:J216.168K
Wikidata:Q83060489
Mol file:3518-76-1.mol

Synonyms:1-Phenethylpiperidin-4-ol;3518-76-1;1-(2-Phenylethyl)piperidin-4-ol;N-phenethyl-4-hydroxy piperidine;1-(2-Phenylethyl)-4-piperidinol;4-Piperidinol,1-(2-phenylethyl)-;EINECS 222-527-7;1-phenethyl-4-hydroxypiperidine;U62RHL2Y72;N-(-PHENETHYL)-4-HYDROXY PIPERIDINE;Cambridge id 5427383;UNII-U62RHL2Y72;Oprea1_163158;4-hydroxy-N-phenethylpiperidine;SCHEMBL4255190;DTXSID90188669;HMS1581O11;MFCD00038874;AKOS009036139;AM85334;CS-0358226;FT-0629317;AB00085107-01;A874729;A1-20323;1-PHENETHYL-4-HYDROXYPIPERIDINE [NFLIS-DRUG]

Suppliers and Price of 1-Phenethylpiperidin-4-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
1-(2-PHENYLETHYL)-4-PIPERIDINOL AldrichCPR
1ea
$ 115.00

Crysdot
1-Phenethylpiperidin-4-ol 95+%
1g
$ 391.00

Chemenu
1-phenethylpiperidin-4-ol 95%
1g
$ 370.00

American Custom Chemicals Corporation
1-PHENETHYLPIPERIDIN-4-OL 95.00%
5MG
$ 504.48

Alichem
1-Phenethylpiperidin-4-ol
1g
$ 391.05

Alichem
1-Phenethylpiperidin-4-ol
250mg
$ 170.64

A1 Biochem Labs
1-Phenethylpiperidin-4-ol 95%
2.5 g
$ 950.00

Total 16 raw suppliers

Chemical Property of 1-Phenethylpiperidin-4-ol

Chemical Property:

Vapor Pressure:2.99E-05mmHg at 25°C
Melting Point:95.5-98.5℃
Boiling Point:341.9°Cat760mmHg
Flash Point:123.8°C
PSA：23.47000
Density:1.064g/cm³
LogP:1.62370
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:205.146664230
Heavy Atom Count:15
Complexity:169

Purity/Quality:

97% ^*data from raw suppliers

1-(2-PHENYLETHYL)-4-PIPERIDINOL AldrichCPR ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(CCC1O)CCC2=CC=CC=C2
Uses 1-Phenethyl-4-piperidinol it is used in preparation of 1-Pyrrolidinyl Indane derivatives as Histamine H3 receptor antagonists useful in treatment of diseases.

Technology Process of 1-Phenethylpiperidin-4-ol

There total 4 articles about 1-Phenethylpiperidin-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 5382-16-1
4-HYDROXYPIPERIDINE

: 103-63-9
1-phenyl-2-bromoethane

: 3518-76-1
(RS)-(+/-)-1-phenethylpiperidin-4-ol

Guidance literature:: With potassium carbonate; In toluene; at 110 ℃;
DOI:10.1016/j.ejmech.2007.06.012

Reference yield: 63.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 18191-59-8
allylsilane

: 2-phenylethan-1-amine, trifluoroacetate

: 3518-76-1
(RS)-(+/-)-1-phenethylpiperidin-4-ol

Guidance literature:: In water; at 58 ℃;
DOI:10.3987/COM-97-8056

Reference yield:

: 5382-16-1
4-HYDROXYPIPERIDINE

: 122-78-1
phenylacetaldehyde

: 3518-76-1
(RS)-(+/-)-1-phenethylpiperidin-4-ol

Guidance literature:: With sodium tris(acetoxy)borohydride; acetic acid; In dichloromethane; at 20 ℃; Inert atmosphere;
DOI:10.1016/j.bioorg.2019.103322