2-Amino-3-(carbamoylamino)oxypropanoic acid

Base Information

• Chemical Name: 2-Amino-3-(carbamoylamino)oxypropanoic acid
• CAS No.: 53459-31-7
• Molecular Formula: C4H9N3O4
• Molecular Weight: 163.132
• NSC Number: 163539
• Mol file: 53459-31-7.mol

Synonyms:NSC163539;NSC-163539

Chemical Property of 2-Amino-3-(carbamoylamino)oxypropanoic acid

Chemical Property:

• Density: 1.493g/cm³
• XLogP3: -4.6
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 163.05930578
• Heavy Atom Count: 11
• Complexity: 159

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(=O)O)N)ONC(=O)N

Technology Process of 2-Amino-3-(carbamoylamino)oxypropanoic acid

There total 6 articles about 2-Amino-3-(carbamoylamino)oxypropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

potassium cyanate (590-28-3) + O-aminoserine methyl ester → O-ureido-L-serine (67799-13-7,53459-31-7)

Guidance literature:

potassium cyanate; O-aminoserine methyl ester; In water; at 20 ℃; for 2h; pH=4 - 5;

With potassium hydroxide; In water; at 20 ℃;

DOI:10.1039/c7ob03013d

Reference yield:

O-acetyl-L-serine (5147-00-2,25248-96-8,44901-25-9) + N-hydroxyurea (127-07-1) → O-ureido-L-serine (67799-13-7,53459-31-7)

Guidance literature:

With BPA-synthase from Citrullus v; K-Pi buffer; at 28 ℃; for 0.5h; pH: 7.5;

DOI:10.1016/S0031-9422(00)82594-7

Reference yield:

(R)-4-amino-3-oxo-isoxazolidine-2-carboxylic acid amide (723726-41-8) → O-ureido-D-serine (53459-31-7)

Guidance literature:

With water;

DOI:10.1021/jm00255a034

upstream raw materials:

O-acetyl-L-serine

N-hydroxyurea

potassium cyanate

D-2-amino-3-(aminooxy)propanoic acid

Downstream raw materials:

S-sulfo-L-cysteine

O-ureido-L-serine