L-Serine, O-[(aminocarbonyl)amino]-

Base Information

• Chemical Name: L-Serine, O-[(aminocarbonyl)amino]-
• CAS No.: 67799-13-7
• Molecular Formula: C4H9N3O4
• Molecular Weight: 163.133
• Mol file: 67799-13-7.mol

Synonyms:(2S)-2-Amino-3-[(carbamoylamino)oxy]propanoate;L-Serine,O-[(aminocarbonyl)amino];O-ureido-L-serine;O-(carbamoylamino)-L-serine;

Chemical Property of L-Serine, O-[(aminocarbonyl)amino]-

Chemical Property:

• PSA: 128.66000
• LogP: -0.39680

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of L-Serine, O-[(aminocarbonyl)amino]-

There total 3 articles about L-Serine, O-[(aminocarbonyl)amino]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

potassium cyanate (590-28-3) + O-aminoserine methyl ester → O-ureido-L-serine (67799-13-7,53459-31-7)

Guidance literature:

potassium cyanate; O-aminoserine methyl ester; In water; at 20 ℃; for 2h; pH=4 - 5;

With potassium hydroxide; In water; at 20 ℃;

DOI:10.1039/c7ob03013d

Reference yield:

O-acetyl-L-serine (5147-00-2,25248-96-8,44901-25-9) + N-hydroxyurea (127-07-1) → O-ureido-L-serine (67799-13-7,53459-31-7)

Guidance literature:

With BPA-synthase from Citrullus v; K-Pi buffer; at 28 ℃; for 0.5h; pH: 7.5;

DOI:10.1016/S0031-9422(00)82594-7

Reference yield:

O-ureido-D-serine (53459-31-7) → O-ureido-L-serine (67799-13-7,53459-31-7)

Guidance literature:

With DcsC; In aq. phosphate buffer; at 30 ℃; for 0.333333h; pH=8.0; Mechanism; Enzymatic reaction;

DOI:10.1128/AAC.02291-12

upstream raw materials:

O-acetyl-L-serine

N-hydroxyurea

O-ureido-D-serine

potassium cyanate

Downstream raw materials:

O-ureido-D-serine

L-Cysteine

S-sulfo-L-cysteine