3-Phenyl-2-(pyridin-3-ylformamido)propanoic acid

Base Information

Chemical Name:3-Phenyl-2-(pyridin-3-ylformamido)propanoic acid
CAS No.:36724-78-4
Molecular Formula:C15H14N2O3
Molecular Weight:270.288
Hs Code.:
NSC Number:351308
DSSTox Substance ID:DTXSID00319846
Mol file:36724-78-4.mol

Synonyms:36724-78-4;3-phenyl-2-(pyridin-3-ylformamido)propanoic acid;3-phenyl-2-(pyridine-3-carbonylamino)propanoic acid;2-(Nicotinamido)-3-phenylpropanoic acid;NSC351308;SCHEMBL2229201;DTXSID00319846;MFCD00420584;AKOS000128185;AKOS016338223;2-(Nicotinamido)-3-phenylpropanoicacid;NSC 351308;NSC-351308;EN300-57174;3-phenyl-2-[(pyridin-3-yl)formamido]propanoic acid;Z239128598;3-Phenyl-2-[(pyridine-3-carbonyl)-amino]-propionic acid

Suppliers and Price of 3-Phenyl-2-(pyridin-3-ylformamido)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3-Phenyl-2-(pyridin-3-ylformamido)propanoic acid

Chemical Property:

Vapor Pressure:1.94E-13mmHg at 25°C
Boiling Point:561.3°Cat760mmHg
Flash Point:293.3°C
Density:1.276g/cm³
XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:270.10044231
Heavy Atom Count:20
Complexity:340

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(C(=O)O)NC(=O)C2=CN=CC=C2

Technology Process of 3-Phenyl-2-(pyridin-3-ylformamido)propanoic acid

There total 17 articles about 3-Phenyl-2-(pyridin-3-ylformamido)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 879123-77-0
3-phenyl-2-[(pyridine-3-carbonyl)amino]propionic acid methyl ester

: 36724-78-4
N-nicotinoyl-DL-phenylalanine

Guidance literature:: 3-phenyl-2-[(pyridine-3-carbonyl)amino]propionic acid methyl ester; With water; lithium hydroxide; In tetrahydrofuran; methanol; at 25 ℃; for 2h;

With hydrogenchloride; In methanol; water;

Reference yield: 94.0%

: 1120-90-7
3-iodopyridine

: Phe-Wang resin

: 18414-58-9
diphenylmethylsilanecarboxylic acid

: 17274-89-4,36724-78-4,74204-45-8
(S)-2-(nicotinamido)-3-phenylpropanoic acid

Guidance literature:: 3-iodopyridine; Phe-Wang resin; diphenylmethylsilanecarboxylic acid; With potassium fluoride; C₃₉H₃₂OP₂*C₁₃H₁₂N^(1-)*Pd⁽²⁺⁾*CH₃O₃S^(1-); triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 15h; wang polystyrene resin Sealed tube; Inert atmosphere;

With triethylsilane; trifluoroacetic acid; In water; at 20 ℃; for 2h; Sealed tube; Inert atmosphere;
DOI:10.1021/acs.orglett.7b01068