DRUPACIN

Base Information

Chemical Name:DRUPACIN
CAS No.:12772-83-7
Molecular Formula:C14H16 O3
Molecular Weight:232.27
Hs Code.:
Mol file:12772-83-7.mol

Synonyms:2-Propenoicacid, 3-(3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-yl)-, (E)-; Drupacin; Dupracine

Suppliers and Price of DRUPACIN

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Dupracine
5g
$ 1320.00

Total 4 raw suppliers

Chemical Property of DRUPACIN

Chemical Property:

PSA：46.53000
LogP:2.88800

Purity/Quality:

99% ^*data from raw suppliers

Dupracine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Dupracine, is a new component of Psoralea drupaceae. It can be used in the synthesis of a series of 2,2-Dimethylchroman-6-ylalkanoic Acids, possessing potential antisickling properties. It is also shown to have growth-inhibitory activities toward Tenebrio molitor.

Technology Process of DRUPACIN

There total 7 articles about DRUPACIN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 61370-75-0
3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-carboxaldehyde

: 141-82-2
malonic acid

: 12772-83-7
3-[2,2-dimethyl-3,4-dihydro-(2H)-benzopyran-6-yl]-2E-propenoic acid

Guidance literature:: With piperidine; In pyridine; for 6h; Heating;
DOI:10.1016/S0968-0896(99)00273-4

Reference yield:

: 123-08-0,65581-83-1
4-hydroxy-benzaldehyde

: 12772-83-7
3-[2,2-dimethyl-3,4-dihydro-(2H)-benzopyran-6-yl]-2E-propenoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: phosphoric acid / Petroleum ether / 24 h / 20 °C

2: piperidine / 2 h / 80 °C

With piperidine; phosphoric acid; In Petroleum ether;
DOI:10.1039/d0nj02125c

Reference yield:

: 78-79-5,9003-31-0
isoprene

: 12772-83-7
3-[2,2-dimethyl-3,4-dihydro-(2H)-benzopyran-6-yl]-2E-propenoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: phosphoric acid / Petroleum ether / 24 h / 20 °C

2: piperidine / 2 h / 80 °C

With piperidine; phosphoric acid; In Petroleum ether;
DOI:10.1039/d0nj02125c