Ethyl 2-(piperazin-1-yl)acetate

Base Information

Chemical Name:Ethyl 2-(piperazin-1-yl)acetate
CAS No.:40004-08-8
Molecular Formula:C8H16N2O2
Molecular Weight:172.227
Hs Code.:2933599090
European Community (EC) Number:254-745-3
DSSTox Substance ID:DTXSID30193070
Nikkaji Number:J261.498G
Wikidata:Q72476838
ChEMBL ID:CHEMBL1221941
Mol file:40004-08-8.mol

Synonyms:40004-08-8;ethyl 2-(piperazin-1-yl)acetate;Ethyl 1-piperazineacetate;1-(Ethoxycarbonylmethyl)piperazine;ethyl piperazin-1-ylacetate;Ethyl piperazinoacetate;ethyl 1-piperazinylacetate;1-Piperazineacetic acid, ethyl ester;ethyl 2-piperazin-1-ylacetate;Ethyl piperazine-1-acetate;2-(Piperazin-1-yl)acetic acid ethyl ester;2-(Piperazin-1-yl)-acetic acid ethyl ester;MFCD00040739;N-(ethoxycarbonylmethyl)piperazine;1-piperazineacetic acid ethyl ester;EINECS 254-745-3;ethyl (piperazin-1-yl)acetate;CID207112;ethyl piperazineacetate;piperazin-1-yl-acetic acid ethyl ester;Ethyl 4-piperazineacetate;SCHEMBL5699;4-carboethoxymethylpiperazine;1-ethoxycarbonylmethylpiperazine;CHEMBL1221941;ethyl2-(piperazin-1-yl)acetate;BDBM36370;Piperazinoacetic acid ethyl ester;AMY3051;DTXSID30193070;CHEBI:188584;ethyl 2-(piperazin-1-yl) acetate;1-(Ethoxycarbonylmethyl)-piperazine;1-(ethoxy carbonylmethyl)-piperazine;1-[(ethoxycarbonyl)methyl]piperazine;STL168023;N-[(ethoxycarbonyl)methyl]-piperazine;AKOS000264276;CS-W010769;PS-5075;Ethyl piperazinoacetate, >=95.0% (GC);Piperazin-1-yl-acetic acid ethyl ester, 8;A6681;FT-0629268;FT-0629269;EN300-24091;5-HEPTYL-2-(4-OCTYLOXYPHENYL)PYRIMIDINE;AB00809285-02;Q-102287;F2158-0956;2-(2-ethylpiperazin-1-yl)acetate;ETHYL 1-PIPERAZINEACETATE

Suppliers and Price of Ethyl 2-(piperazin-1-yl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(Ethoxycarbonylmethyl)piperazine
1g
$ 60.00

SynQuest Laboratories
Ethyl (piperazin-1-yl)acetate
1 g
$ 16.00

Sigma-Aldrich
Ethyl piperazinoacetate ≥95.0% (GC)
25 g
$ 350.00

Sigma-Aldrich
Ethyl piperazinoacetate ≥95.0% (GC)
25g-f
$ 331.00

Sigma-Aldrich
Ethyl piperazinoacetate ≥95.0% (GC)
5 g
$ 89.70

Sigma-Aldrich
Ethyl piperazinoacetate ≥95.0% (GC)
5g-f
$ 84.90

Medical Isotopes, Inc.
N-(Ethoxycarbonylmethyl)piperazine
100 mg
$ 640.00

Matrix Scientific
Ethyl piperazin-1-ylacetate 97%
10g
$ 252.00

Matrix Scientific
Ethyl piperazin-1-ylacetate 97%
1g
$ 56.00

Crysdot
Ethyl2-(piperazin-1-yl)acetate 95+%
100g
$ 400.00

Total 52 raw suppliers

Chemical Property of Ethyl 2-(piperazin-1-yl)acetate

Chemical Property:

Vapor Pressure:0.0193mmHg at 25°C
Refractive Index:n20/D 1.472
Boiling Point:252.473 °C at 760 mmHg
PKA:8.96±0.10(Predicted)
Flash Point:106.492 °C
PSA：41.57000
Density:1.027 g/cm³
LogP:-0.27860
Storage Temp.:?20°C
Sensitive.:Air Sensitive
Solubility.:Chloroform, Methanol
Water Solubility.:Soluble in water, chloroform, and methanol.
XLogP3:-0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:172.121177757
Heavy Atom Count:12
Complexity:144

Purity/Quality:

99%, ^*data from raw suppliers

N-(Ethoxycarbonylmethyl)piperazine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCOC(=O)CN1CCNCC1
Uses 1-(ETHOXYCARBONYLMETHYL)PIPERAZINE is used in the preparation of aralkylpiperazine- and aryl-substituted hydrazines, particularly benzylpiperazineacetyl hydrazones of hydroxyaryl aldehydes, as selecti ve inducers of apoptosis and activators of procaspases for use as anticancer agents. N-(Ethoxycarbonylmethyl)piperazine is used in the preparation of aralkylpiperazine- and aryl-substituted hydrazines, particularly benzylpiperazineacetyl hydrazones of hydroxyaryl aldehydes, as selective inducers of apoptosis and activators of procaspases for use as anticancer agents.

Technology Process of Ethyl 2-(piperazin-1-yl)acetate

There total 6 articles about Ethyl 2-(piperazin-1-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%