1-PYRIDIN-2-YL-ETHYLAMINE

Base Information

• Chemical Name: 1-PYRIDIN-2-YL-ETHYLAMINE
• CAS No.: 42088-91-5
• Molecular Formula: C7H10 N2
• Molecular Weight: 122.17
• Hs Code.: 2933399090
• Mol file: 42088-91-5.mol

Synonyms:(?à)-2-(1-Aminoethyl)pyridine;1-(2-Pyridinyl)ethanamine; 1-(2-Pyridyl)ethanamine; 1-(2-Pyridyl)ethylamine;1-(Pyridin-2-yl)ethylamine; 2-(1-Aminoethyl)pyridine

Chemical Property of 1-PYRIDIN-2-YL-ETHYLAMINE

Chemical Property:

• Vapor Pressure: 0.44mmHg at 25°C
• Refractive Index: n20/D1.528
• Boiling Point: 194.5 °C at 760 mmHg
• PKA: 9.05±0.39(Predicted)
• Flash Point: 92.1 °C
• PSA: 38.91000
• Density: 1.018 g/cm³
• LogP: 1.80160
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Sensitive.: Air Sensitive

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Pyridin-2-yl-ethylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): TXi
• Hazard Codes: T,Xi
• Statements: 25-37/38-41
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-PYRIDIN-2-YL-ETHYLAMINE

There total 4 articles about 1-PYRIDIN-2-YL-ETHYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(6-chloro-pyridin-2-yl)-N'-(1-pyridin-2-yl-ethylidene)-hydrazine → 6-chloropyridin-2-amine (45644-21-1) + 2-aminoethylpyridine (42088-91-5)

Guidance literature:

In ethanol; water; pH=1.7; Further Variations:; pH-values; Kinetics; Electrolysis;

DOI:10.1007/s00706-005-0447-z

Reference yield:

2-acetylpyridine (1122-62-9) + 1,4-diaminobutane (110-60-1) → 1-pyrroline (5724-81-2) + (S)-1-(2-pyridyl)ethylamine (27854-90-6) + (R)-1-(pyridin-2-yl)ethanamine (27854-90-6,42088-91-5,42732-17-2,45695-03-2)

Guidance literature:

With spuC gene from Pseudomonas chlororaphis subsp. aureofaciens; In dimethyl sulfoxide; at 40 ℃; for 24h; pH=9; enantioselective reaction; Enzymatic reaction;

DOI:10.1039/c6gc02102f

Reference yield:

2-acetylpyridine (1122-62-9) + bishydrochloride salt of cis-1,4-diamino-but-2-ene (87227-77-8,99240-70-7,114118-70-6,119874-79-2) → pyrrole (109-97-7,30604-81-0) + (R)-1-(pyridin-2-yl)ethanamine (27854-90-6,42088-91-5,42732-17-2,45695-03-2)

Guidance literature:

With transaminase ATA-025; In aq. phosphate buffer; dimethyl sulfoxide; at 30 ℃; for 48h; pH=7.5; Enzymatic reaction;

DOI:10.1002/adsc.201501066

upstream raw materials:

2-acetylpyridine

bishydrochloride salt of cis-1,4-diamino-but-2-ene

1,4-diaminobutane

Downstream raw materials:

C₃₅H₃₇N₇O₃S

Refernces

• 1、 Martínez-Montero, Lía,Gotor, Vicente,Gotor-Fernández, Vicente,Lavandera, Iván. "But-2-ene-1,4-diamine and But-2-ene-1,4-diol as Donors for Thermodynamically Favored Transaminase- and Alcohol Dehydrogenase-Catalyzed Processes". supporting information. p. 1618 - 1624. Retrieved 2016/10/13.
• 2、 -. "PYRAZOLE DERIVATIVES AS INHIBITORS OF RECEPTOR TYROSYNE KINASES". Page/Page column 98. . Retrieved 2008/06/13.