3-(Cyclohex-1-en-1-yl)acrylic acid

Base Information

• Chemical Name: 3-(Cyclohex-1-en-1-yl)acrylic acid
• CAS No.: 56453-88-4
• Molecular Formula: C9H12O2
• Molecular Weight: 152.193
• NSC Number: 244956
• Nikkaji Number: J1.080.549J,J569.978I
• Mol file: 56453-88-4.mol

Synonyms:3-(Cyclohex-1-en-1-yl)acrylic acid;56453-88-4;65173-41-3;(E)-3-(cyclohexen-1-yl)prop-2-enoic acid;(E)-3-(Cyclohex-1-en-1-yl)acrylic acid;3-CYCLOHEX-1-ENYL-ACRYLIC ACID;(E)-3-(1-cyclohexenyl)prop-2-enoic acid;NSC244956;SCHEMBL471180;3-(1-Cyclohexenyl)acrylic acid;(E)-3-(1-Cyclohexenyl)acrylic acid;AKOS006279995;NSC-244956;(E)-3-(cyclohex-1-en-1-yl)acrylicacid;BS-46283;CS-0163254;Tricyclo[8.2.2.24,7]hexadeca-4,6,10,12,13,15-hexaene-5,6,11,12-tetracarbonitrile, stereoisomer

Chemical Property of 3-(Cyclohex-1-en-1-yl)acrylic acid

Chemical Property:

• Vapor Pressure: 0.000127mmHg at 25°C
• Boiling Point: 311.1°Cat760mmHg
• Flash Point: 216.1°C
• Density: 1.186g/cm³
• XLogP3: 2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 152.083729621
• Heavy Atom Count: 11
• Complexity: 202

Purity/Quality:

99.3% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CCC(=CC1)C=CC(=O)O
• Isomeric SMILES: C1CCC(=CC1)/C=C/C(=O)O

Technology Process of 3-(Cyclohex-1-en-1-yl)acrylic acid

There total 25 articles about 3-(Cyclohex-1-en-1-yl)acrylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(E)-3-(1-cyclohexen-1-yl)-2-propenoic acid ethyl ester (75567-08-7) → (E)-3-(1-cyclohexen-1-yl)-2-propenoic acid (56453-88-4)

Guidance literature:

With water; sodium hydroxide; In ethanol; at 20 ℃; for 12h;

DOI:10.1016/j.phytochem.2012.08.001

Reference yield: 87.0%

(E)-3-(cyclohex-1-en-1-yl)acrylaldehyde (102651-85-4) → (E)-3-(1-cyclohexen-1-yl)-2-propenoic acid (56453-88-4)

Guidance literature:

With potassium hydroxide; silver nitrate; In ethanol; water; Ambient temperature;

Reference yield: 86.0%

1-ethenylcyclohexene (931-49-7) + carbon dioxide (124-38-9,18923-20-1) → (E)-3-(1-cyclohexen-1-yl)-2-propenoic acid (56453-88-4)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at 0 ℃; for 2h; under 760 Torr;

DOI:10.1021/jo982443f

upstream raw materials:

2-Ethoxy-spiro[2.5]octane-1-carboxylic acid ethyl ester

2-Allyloxyspiro<2.5>octan-1-carbonsaeureaethylester

carbon monoxide

trans-2-(1-Cyclohexenyl)ethenylmercuric chloride

Downstream raw materials:

(E)-3-(cyclohex-1-ene)-prop-2-enoic acid methyl ester

1,1-dimethyl<(2R,6S)-2-<(1E,3Z,5S)-5-hydroxy-1,3-hexadienyl>-6-methyl-1-piperidine>carboxylate

(1S,2Z)-<1-methyl-5-(trimethylsilyl)-2-penten-4-ynyl>-3-<(2E)-1-cyclohexen-1-yl>-2-propenoate

(E)-3-Cyclohex-1-enyl-acrylic acid (Z)-1-methyl-6-(tetrahydro-pyran-2-yloxy)-hex-2-en-4-ynyl ester