n-(4-Chlorobutanoyl)glycine

Base Information

Chemical Name:n-(4-Chlorobutanoyl)glycine
CAS No.:64026-50-2
Molecular Formula:C₆H₁₀ClNO₃
Molecular Weight:179.603
Hs Code.:
NSC Number:118693
DSSTox Substance ID:DTXSID90297861
Wikidata:Q82039340

Synonyms:64026-50-2;n-(4-chlorobutanoyl)glycine;NSC118693;SCHEMBL11715820;DTXSID90297861;NSC-118693

Suppliers and Price of n-(4-Chlorobutanoyl)glycine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of n-(4-Chlorobutanoyl)glycine

Chemical Property:

Vapor Pressure:7.33E-09mmHg at 25°C
Boiling Point:437.1°Cat760mmHg
Flash Point:218.1°C
Density:1.287g/cm³
XLogP3:0
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:179.0349209
Heavy Atom Count:11
Complexity:149

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(CC(=O)NCC(=O)O)CCl

Technology Process of n-(4-Chlorobutanoyl)glycine

There total 2 articles about n-(4-Chlorobutanoyl)glycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 56-40-6,18875-39-3,25718-94-9
glycine

: 4635-59-0
4-Chlorobutanoyl chloride

: 64026-50-2
2-(4-chlorobutanamido)acetic acid

Guidance literature:: In tetrahydrofuran; at 0 ℃; for 2.5h; Reflux; Inert atmosphere;
DOI:10.1039/c2ob25996f

Reference yield:

: 64026-50-2
2-(4-chlorobutanamido)acetic acid

Guidance literature:: Glycin, Trimethylchlorsilan, NEt3, 4-Chlorbuttersaeurechlorid;

Reference yield:

: 64026-50-2
2-(4-chlorobutanamido)acetic acid

: 1401355-47-2
S-phenyl 2-(4-azidobutanamido)ethanethioate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium azide / N,N-dimethyl-formamide / 24 h / 80 °C / Inert atmosphere

2.1: 4-methyl-morpholine; isobutyl chloroformate / tetrahydrofuran / 0.08 h / 0 °C / Inert atmosphere

2.2: 24 h / 20 °C / Inert atmosphere

With 4-methyl-morpholine; sodium azide; isobutyl chloroformate; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1039/c2ob25996f