(1R,2R)-N-BOC-1-AMINO-2-PHENYLCYCLOPROPANECARBOXYLIC ACID

Base Information

Chemical Name:(1R,2R)-N-BOC-1-AMINO-2-PHENYLCYCLOPROPANECARBOXYLIC ACID
CAS No.:180322-86-5
Molecular Formula:C15H19 N O4
Molecular Weight:277.32
Hs Code.:2922498590
Mol file:180322-86-5.mol

Synonyms:Cyclopropanecarboxylicacid, 1-[[(1,1-dimethylethoxy)carbonyl]amino]-2-phenyl-, (1R-cis)-

Suppliers and Price of (1R,2R)-N-BOC-1-AMINO-2-PHENYLCYCLOPROPANECARBOXYLIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Atlantic Research Chemicals
(1R,2R)-1-[(tert-Butoxycarbonyl)amino]-2-phenylcyclopropanecarboxylicacid 95%
1gm:
$ 1410.29

American Custom Chemicals Corporation
(1R,2R)-N-BOC-1-AMINO-2-PHENYLCYCLOPROPANECARBOXYLIC ACID 95.00%
50MG
$ 647.61

Total 3 raw suppliers

Chemical Property of (1R,2R)-N-BOC-1-AMINO-2-PHENYLCYCLOPROPANECARBOXYLIC ACID

Chemical Property:

Vapor Pressure:6.78E-09mmHg at 25°C
Melting Point:180-182 °C
Refractive Index:1.5080 (estimate)
Boiling Point:450.3°Cat760mmHg
Flash Point:226.1°C
PSA：75.63000
Density:1.22g/cm³
LogP:2.91290

Purity/Quality:

99%, ^*data from raw suppliers

(1R,2R)-1-[(tert-Butoxycarbonyl)amino]-2-phenylcyclopropanecarboxylicacid 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 37/39-26

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (1R,2R)-N-BOC-1-AMINO-2-PHENYLCYCLOPROPANECARBOXYLIC ACID

There total 4 articles about (1R,2R)-N-BOC-1-AMINO-2-PHENYLCYCLOPROPANECARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 180322-85-4
(1R,2R)-1-tert-Butoxycarbonylamino-2-phenyl-cyclopropanecarboxylic acid methyl ester

: 180322-86-5
(1R,2R)-1-tert-Butoxycarbonylamino-2-phenyl-cyclopropanecarboxylic acid

Guidance literature:: With potassium hydroxide; In tetrahydrofuran; Ambient temperature;
DOI:10.1021/ja9604931

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 180322-86-5
(1R,2R)-1-tert-Butoxycarbonylamino-2-phenyl-cyclopropanecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 2-methyl-propan-2-ol; hexane / Heating

2: 90 percent / aq. KOH / tetrahydrofuran / Ambient temperature

With potassium hydroxide; In tetrahydrofuran; hexane; tert-butyl alcohol;
DOI:10.1021/ja9604931

Reference yield:

: 110769-84-1,123039-88-3,197778-15-7
methyl (1R,2R)-1-amino-2-phenylcyclopropanecarboxylate

: 180322-86-5
(1R,2R)-1-tert-Butoxycarbonylamino-2-phenyl-cyclopropanecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 2-methyl-propan-2-ol; hexane / Heating

2: 90 percent / aq. KOH / tetrahydrofuran / Ambient temperature

With potassium hydroxide; In tetrahydrofuran; hexane; tert-butyl alcohol;
DOI:10.1021/ja9604931