2-((4-Methyl-2-oxo-2H-chromen-7-yl)oxy)acetohydrazide

Base Information

Chemical Name:2-((4-Methyl-2-oxo-2H-chromen-7-yl)oxy)acetohydrazide
CAS No.:69321-36-4
Molecular Formula:C12H12N2O4
Molecular Weight:248.238
Hs Code.:2932209090
DSSTox Substance ID:DTXSID90219381
Nikkaji Number:J582.921F
Wikidata:Q83096303
ChEMBL ID:CHEMBL2178986
Mol file:69321-36-4.mol

Synonyms:69321-36-4;2-((4-Methyl-2-oxo-2H-chromen-7-yl)oxy)acetohydrazide;(4-Methyl-2-oxo-2H-chromen-7-yloxy)-acetic acid hydrazide;2-[(4-Methyl-2-oxo-2H-chromen-7-yl)oxy]acetohydrazide;2-(4-methyl-2-oxochromen-7-yl)oxyacetohydrazide;CHEMBL2178986;Acetic acid, ((4-methyl-2-oxo-2H-1-benzopyran-7-yl)oxy)-, hydrazide;MFCD01171554;Acetic acid, [(4-methyl-2-oxo-2H-1-benzopyran-7-yl)oxy]-, hydrazide;2-[(4-Methyl-2-oxo-2H-chromen-7-yl)oxy]-acetohydrazide;Oprea1_446462;Oprea1_784269;DTXSID90219381;UFDAEMFJMQOINV-UHFFFAOYSA-N;BDBM50400134;STK871101;AKOS000116773;SB86514;LS-04889;UPCMLD0ENAT0506-4355:001;CS-0219374;FT-0684268;EN300-03837;Acethydrazide, 2-(4-methyl-7-coumarinyloxy)-;Coumarin, 4-methyl-7-[2-oxo-2-hydrazinoethoxy]-;Z56813541;2-(4-methyl-2-oxo-2h-chromen-7-yloxy) acetohydrazide;2-[(4-Methyl-2-oxo-2H-chromen-7-yl)oxy]acetohydrazide #;[(4-Methyl-2-oxo-2H-1-benzopyran-7-yl)oxy]acetic acid hydrazide

Suppliers and Price of 2-((4-Methyl-2-oxo-2H-chromen-7-yl)oxy)acetohydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-[(4-Methyl-2-oxo-2H-chromen-7-yl)oxy]-acetohydrazide
500mg
$ 158.00

Crysdot
2-((4-Methyl-2-oxo-2H-chromen-7-yl)oxy)acetohydrazide 95+%
5g
$ 499.00

Chemenu
2-((4-Methyl-2-oxo-2H-chromen-7-yl)oxy)acetohydrazide 95%
5g
$ 471.00

American Custom Chemicals Corporation
(4-METHYL-2-OXO-2H-CHROMEN-7-YLOXY)-ACETIC ACID HYDRAZIDE 95.00%
5G
$ 1168.42

American Custom Chemicals Corporation
(4-METHYL-2-OXO-2H-CHROMEN-7-YLOXY)-ACETIC ACID HYDRAZIDE 95.00%
2.5G
$ 983.88

American Custom Chemicals Corporation
(4-METHYL-2-OXO-2H-CHROMEN-7-YLOXY)-ACETIC ACID HYDRAZIDE 95.00%
1G
$ 721.57

Alichem
2-((4-Methyl-2-oxo-2H-chromen-7-yl)oxy)acetohydrazide
5g
$ 504.00

AK Scientific
2-[(4-Methyl-2-oxo-2H-chromen-7-yl)oxy]-acetohydrazide
2.5g
$ 537.00

Total 3 raw suppliers

Chemical Property of 2-((4-Methyl-2-oxo-2H-chromen-7-yl)oxy)acetohydrazide

Chemical Property:

Vapor Pressure:1.78E-12mmHg at 25°C
Boiling Point:557.8°C at 760 mmHg
Flash Point:291.1°C
PSA：94.56000
Density:1.34g/cm³
LogP:1.56130
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:248.07970687
Heavy Atom Count:18
Complexity:380

Purity/Quality:

97% ^*data from raw suppliers

2-[(4-Methyl-2-oxo-2H-chromen-7-yl)oxy]-acetohydrazide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=O)OC2=C1C=CC(=C2)OCC(=O)NN
General Description (4-METHYL-2-OXO-2H-CHROMEN-7-YLOXY)-ACETIC ACID HYDRAZIDE is a derivative of 4-methylcoumarin with demonstrated antioxidant properties, exhibiting strong free radical scavenging activity against DPPH, nitric oxide, and hydrogen peroxide, as well as ferric-reducing antioxidant power (FRAP). Its mechanism of action is supported by quantum chemical studies, including HOMO-LUMO analysis, which highlight its potential as an effective antioxidant. Additionally, it serves as a key intermediate in the synthesis of antimicrobial thiazolidinone derivatives, indicating its versatility in medicinal chemistry applications. **Returned paragraph:** (4-METHYL-2-OXO-2H-CHROMEN-7-YLOXY)-ACETIC ACID HYDRAZIDE is a 4-methylcoumarin derivative with notable antioxidant activity, including free radical scavenging and ferric-reducing capabilities, supported by computational studies. It also acts as a precursor for synthesizing antimicrobial thiazolidinone compounds, underscoring its dual utility in antioxidant and medicinal chemistry research.

Technology Process of 2-((4-Methyl-2-oxo-2H-chromen-7-yl)oxy)acetohydrazide

There total 9 articles about 2-((4-Methyl-2-oxo-2H-chromen-7-yl)oxy)acetohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.6%