2-Hydroxycyclododecanone

Base Information

• Chemical Name: 2-Hydroxycyclododecanone
• CAS No.: 19025-38-8
• Molecular Formula: C₁₂H₂₂O₂
• Molecular Weight: 198.305
• European Community (EC) Number: 633-773-3
• NSC Number: 118877
• DSSTox Substance ID: DTXSID90297886
• Nikkaji Number: J918.776F
• Mol file: 19025-38-8.mol

Synonyms:2-hydroxycyclododecanone;19025-38-8;NSC118877;2-hydroxy-cyclododecan-1-one;SCHEMBL5374326;DTXSID90297886;AKOS024333998;NSC-118877

Chemical Property of 2-Hydroxycyclododecanone

Chemical Property:

• Vapor Pressure: 1.08E-05mmHg at 25°C
• Boiling Point: 332.1°Cat760mmHg
• Flash Point: 141.1°C
• Density: 0.96g/cm³
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 198.161979940
• Heavy Atom Count: 14
• Complexity: 166

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1CCCCCC(=O)C(CCCC1)O

Technology Process of 2-Hydroxycyclododecanone

There total 7 articles about 2-Hydroxycyclododecanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

α-iodocyclododecanone (69381-33-5) → 2-hydroxycyclododecanone (19025-38-8,140134-30-1) + cyclododecanone (830-13-7)

Guidance literature:

In hexane; water; at 20 ℃; for 576h; Irradiation;

DOI:10.1016/S0040-4039(99)02010-9

Reference yield: 19.9%

1,2-epoxycyclododecane (286-99-7) → 2-hydroxycyclododecanone (19025-38-8,140134-30-1) + cyclododecanone (830-13-7)

Guidance literature:

With 4 A molecular sieve; dimethyl sulfoxide; tetrafluoroboric acid dimethyl ether complex; at 100 ℃; for 9h; in a sealed tube;

DOI:10.1246/bcsj.62.645

Reference yield: 3.1%

2-Acetoxycyclododecanone (26307-31-3) → 1,12-dodecanedioic acid (693-23-2) + 2-hydroxycyclododecanone (19025-38-8,140134-30-1)

Guidance literature:

With potassium hydroxide; In methanol;

upstream raw materials:

1,2-epoxycyclododecane

2-Acetoxycyclododecanone

2-bromocyclododecan-1-one

α-iodocyclododecanone

Downstream raw materials:

cyclododecanone

1,12-dodecanedioic acid

2-chlorocyclododecanone

1,4-dioxacyclohexadecane-5,16-dione