N,N-Dimethyl-9-methoxy-5-nitropyrazolo(3,4,5-kl)acridine-2(6H)-ethanamine

Base Information

Chemical Name:N,N-Dimethyl-9-methoxy-5-nitropyrazolo(3,4,5-kl)acridine-2(6H)-ethanamine
CAS No.:99008-57-8
Molecular Formula:C₁₈H₁₉N₅O₃
Molecular Weight:353.381
Hs Code.:
DSSTox Substance ID:DTXSID10912903
Nikkaji Number:J577.807G
Wikidata:Q82883354
ChEMBL ID:CHEMBL117728

Synonyms:BRN 5912472;PD 114,245;N,N-Dimethyl-9-methoxy-5-nitropyrazolo(3,4,5-kl)acridine-2(6H)-ethanamine;Pyrazolo(3,4,5-kl)acridine-2(6H)-ethanamine, N,N-dimethyl-9-methoxy-5-nitro-;99008-57-8;CHEMBL117728;SCHEMBL10850685;DTXSID10912903;LS-128927;2-(9-Methoxy-5-nitropyrazolo[3,4,5-kl]acridin-2(1H)-yl)-N,N-dimethylethan-1-amine;N,N-Dimethyl-5-nitro-9-methoxypyrazolo[3,4,5-kl]acridine-2(6H)-(ethanamine)

Suppliers and Price of N,N-Dimethyl-9-methoxy-5-nitropyrazolo(3,4,5-kl)acridine-2(6H)-ethanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N,N-Dimethyl-9-methoxy-5-nitropyrazolo(3,4,5-kl)acridine-2(6H)-ethanamine

Chemical Property:

Vapor Pressure:1.06E-13mmHg at 25°C
Boiling Point:585.6°Cat760mmHg
PKA:8.70±0.28(Predicted)
Flash Point:308°C
PSA：91.90000
Density:1.343g/cm³
LogP:3.67240
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:353.14878949
Heavy Atom Count:26
Complexity:527

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CCN1C2=C3C(=C(C=C2)[N+](=O)[O-])NC4=C(C3=N1)C=C(C=C4)OC

Technology Process of N,N-Dimethyl-9-methoxy-5-nitropyrazolo(3,4,5-kl)acridine-2(6H)-ethanamine

There total 5 articles about N,N-Dimethyl-9-methoxy-5-nitropyrazolo(3,4,5-kl)acridine-2(6H)-ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 21814-48-2
1-chloro-7-methoxy-4-nitro-10H-acridin-9-one

: 1754-57-0
(2-dimethylaminoethyl)hydrazine

: 99008-57-8
9-methoxy-N,N-dimethyl-5-nitropyrazolo[3,4,5-kl]acridine-2(6H)-ethanamine

Guidance literature:: In tetrahydrofuran; methanol; for 18h; Ambient temperature;
DOI:10.1021/jm00104a001

Reference yield:

: 55775-97-8
2,6-dichloro-3-nitrobenzoic acid

: 99008-57-8
9-methoxy-N,N-dimethyl-5-nitropyrazolo[3,4,5-kl]acridine-2(6H)-ethanamine

Guidance literature:: Multi-step reaction with 3 steps

1: 83 percent / N,N-dimethylaniline / 18 h / Heating

2: 88 percent / N,N-dimethylaniline, POCl₃ / 1,2-dichloro-ethane / 18 h / Heating

3: 70 percent / tetrahydrofuran; methanol / 18 h / Ambient temperature

With N,N-dimethyl-aniline; trichlorophosphate; In tetrahydrofuran; methanol; 1,2-dichloro-ethane;
DOI:10.1021/jm00104a001

Reference yield:

: 55776-09-5
6-chloro-2-<(4-methoxyphenyl)amino>-3-nitrobenzoic acid

: 99008-57-8
9-methoxy-N,N-dimethyl-5-nitropyrazolo[3,4,5-kl]acridine-2(6H)-ethanamine

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / N,N-dimethylaniline, POCl₃ / 1,2-dichloro-ethane / 18 h / Heating

2: 70 percent / tetrahydrofuran; methanol / 18 h / Ambient temperature

With N,N-dimethyl-aniline; trichlorophosphate; In tetrahydrofuran; methanol; 1,2-dichloro-ethane;
DOI:10.1021/jm00104a001