1754-57-0

Usage

Hazard

A poison. Moderately toxic by ingestion and inhalation.

InChI:InChI=1/C4H13N3/c1-7(2)4-3-6-5/h6H,3-5H2,1-2H3

Upstream product

• 107-99-3 2-(dimethylamino)ethyl chloride 
• 4584-46-7 (2-chloroethyl)dimethylamine hydrochloride 

Downstream Products

• 51244-52-1 6-(2-dimethylamino-ethyl)-3,4-dimethyl-6H-isoxazolo[3,4-d]pyridazin-7-one 
• 51244-58-7 6-(2-dimethylamino-ethyl)-4-phenyl-6H-isoxazolo[3,4-d]pyridazin-7-one 
• 51244-55-4 6-(2-dimethylamino-ethyl)-3-methyl-4-phenyl-6H-isoxazolo[3,4-d]pyridazin-7-one 
• 99008-57-8 9-methoxy-N,N-dimethyl-5-nitropyrazolo[3,4,5-kl]acridine-2(6H)-ethanamine 
• 69982-35-0 4-[6-(2-Chloro-4-methoxyphenoxy)hexyl]-1-(2-dimethylaminoethyl)-3,5-diethyl-1H-pyrazole 
• 107589-99-1 2-<β-(dimethylamino)ethyl>-4-phenylsemicarbazide 
• 107590-02-3 1,6-diphenyl-2-<β-(dimethylamino)ethyl>diurea 
• 107590-05-6 2,4-toluylenedi<2-(β-dimethylaminoethyl)-4-semicarbazide> 
• 107590-03-4 4,4'-diphenylmethanedi<2-(β-dimethylaminoethyl)-4-semicarbazide> 
• 172779-28-1 5-chloro-2-[2-(dimethylamino)ethyl]-10-(p-methoxybenzyloxy)isoquino[5,6,7-cd]indazole-6(2H)-one 
• 214976-43-9 5-Chloro-2-(2-dimethylamino-ethyl)-7-(4-methoxy-benzyloxy)-2H-1,2,9-triaza-aceanthrylen-6-one 
• 156090-03-8 2-<2-(dimethylamino)ethyl>-5-<<(4-methylphenyl)sulfonyl>oxy>indazolo<4,3-gh>isoquinolin-6(2H)-one 
• 630129-38-3 8,11-di(benzyloxy)-6-chloro-2-[2-(dimethylamino)ethyl]-2,7-dihydro-3H-dibenzo[de,h]cinnoline-3,7-dione 
• 1567543-60-5 C₁₁H₁₇N₃ 

Relevant academic research and scientific papers

Hypoxia activated prodrugs of a 9-aza-anthrapyrazole derivative that has promising anticancer activity

Mono- and bis-N-oxides of a 9-aza-anthrapyrazole derivative having two 2-(dimethylamino)ethyl appendages were prepared by using a mild oxaziridine reagent. Biochemical and cell culture assays indicate that the bis-oxide is an inactive prodrug that readily converts to the active parent molecule under hypoxic conditions that are analogous to those present within certain tumors.

2-Pyrazolin-5-ones bearing a basic dialkylaminoalkyl substituent at the N1-position: Preparation and NMR spectroscopic investigations

2-Pyrazolin-5-ones (= tautomers to 5-hydroxypyrazols) bearing dialkylaminoyalkyl substituents at the ring nitrogen atom N-1 are prepared from the corresponding hydrazines and beta-ketoesters. Detailed NMR spectroscopic investigations (1H,

Synthesis of 9,10-anthraquinone monoalkylaminoalkylhydrazones as potential antitumor drugs

In the constant search for new compounds endowed with antitumor activity we have synthesized a series of anthraquinone hydrazones, which can be seen either as opened-cycle modified anthrapyrazoles or as chromophore-modified anthracenediones. Seven 9,10-anthraquinone monoalkylaminoalkylhydrazones (3c-i) were synthesized from 10,10-dibromoanthrone (4) and a suitable N-alkylhydrazine. The hydrazones were converted into hydrochlorides and tested for their cytotoxic activity against L1210 murine leukemia cells. Two of them possess marginal activity in vitro.

3-aryl-7-chloro-3,4-dihydroacridine-1,9(2H,10H)-dione 1-oximes and 1-hydrazone derivatives, their salts, a process for their preparation, agents containing them and their use

3-Aryl-7-chloro-3,4-dihydroacridine-1,9(2H,10H)-dione 1-oximes and 1-hydrazone derivatives of the formula I STR1 and their physiologically tolerated acid addition and ammonium salts are described, as is a process for their preparation. The new compounds are chemotherapeutic agents and are active against protozoa, especially malaria plasmodia.