1754-57-0

Basic information

• Product Name: 2-hydrazinyl-N,N-dimethyl-ethanamine
• Synonyms: 2-hydrazinyl-N,N-dimethyl-ethanamine
• CAS NO: 1754-57-0
• Molecular Formula: C₄H₁₃N₃
• Molecular Weight: 103.20
• Mol File: 1754-57-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 185.3°Cat760mmHg
• Flash Point: 65.9°C
• Appearance: /
• Density: 0.902g/cm³
• Vapor Pressure: 0.701mmHg at 25°C
• Refractive Index: 1.462
• CAS DataBase Reference: 2-hydrazinyl-N,N-dimethyl-ethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydrazinyl-N,N-dimethyl-ethanamine(1754-57-0)
• EPA Substance Registry System: 2-hydrazinyl-N,N-dimethyl-ethanamine(1754-57-0)

Safety Data

• Hazardous Substances Data: 1754-57-0(Hazardous Substances Data)

Usage

Hazard

A poison. Moderately toxic by ingestion and inhalation.

InChI:InChI=1/C4H13N3/c1-7(2)4-3-6-5/h6H,3-5H2,1-2H3

Upstream product

• 4584-46-7 (2-chloroethyl)dimethylamine hydrochloride 
• 107-99-3 2-(dimethylamino)ethyl chloride 

Downstream Products

• 51244-52-1 6-(2-dimethylamino-ethyl)-3,4-dimethyl-6H-isoxazolo[3,4-d]pyridazin-7-one 
• 107590-03-4 4,4'-diphenylmethanedi<2-(β-dimethylaminoethyl)-4-semicarbazide> 
• 1567543-62-7 C₁₂H₁₇N₃O₂ 
• 1567543-61-6 C₁₁H₁₇N₃O 
• 1567543-60-5 C₁₁H₁₇N₃ 
• 1403362-02-6 2-[2-(dimethylamino)ethyl]-5-chloro-2,7-dihydro-3H-dibenzo[de,h]cynnoline-3,7-dione 
• 1099657-60-9 C₁₅H₁₇Cl₃N₆O 
• 156090-03-8 2-<2-(dimethylamino)ethyl>-5-<<(4-methylphenyl)sulfonyl>oxy>indazolo<4,3-gh>isoquinolin-6(2H)-one 
• 630129-38-3 8,11-di(benzyloxy)-6-chloro-2-[2-(dimethylamino)ethyl]-2,7-dihydro-3H-dibenzo[de,h]cinnoline-3,7-dione 
• 214976-43-9 5-Chloro-2-(2-dimethylamino-ethyl)-7-(4-methoxy-benzyloxy)-2H-1,2,9-triaza-aceanthrylen-6-one 
• 172779-28-1 5-chloro-2-[2-(dimethylamino)ethyl]-10-(p-methoxybenzyloxy)isoquino[5,6,7-cd]indazole-6(2H)-one 
• 107590-05-6 2,4-toluylenedi<2-(β-dimethylaminoethyl)-4-semicarbazide> 
• 107589-99-1 2-<β-(dimethylamino)ethyl>-4-phenylsemicarbazide 
• 107590-02-3 1,6-diphenyl-2-<β-(dimethylamino)ethyl>diurea 

Relevant articles and documents

Hypoxia activated prodrugs of a 9-aza-anthrapyrazole derivative that has promising anticancer activity

Mono- and bis-N-oxides of a 9-aza-anthrapyrazole derivative having two 2-(dimethylamino)ethyl appendages were prepared by using a mild oxaziridine reagent. Biochemical and cell culture assays indicate that the bis-oxide is an inactive prodrug that readily converts to the active parent molecule under hypoxic conditions that are analogous to those present within certain tumors.

Synthesis of 9,10-anthraquinone monoalkylaminoalkylhydrazones as potential antitumor drugs

In the constant search for new compounds endowed with antitumor activity we have synthesized a series of anthraquinone hydrazones, which can be seen either as opened-cycle modified anthrapyrazoles or as chromophore-modified anthracenediones. Seven 9,10-anthraquinone monoalkylaminoalkylhydrazones (3c-i) were synthesized from 10,10-dibromoanthrone (4) and a suitable N-alkylhydrazine. The hydrazones were converted into hydrochlorides and tested for their cytotoxic activity against L1210 murine leukemia cells. Two of them possess marginal activity in vitro.

SYNTHESIS AND BIOLOGICAL PROPERTIES OF AMINOALKYLHYDRAZINES. A UNIQUE

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