4-(4-chlorophenyl)sulfonyl-5-(3,4-dihydro-1H-isoquinolin-2-yl)-2-thiophen-2-yl-1,3-oxazole

Base Information Edit

Chemical Name:4-(4-chlorophenyl)sulfonyl-5-(3,4-dihydro-1H-isoquinolin-2-yl)-2-thiophen-2-yl-1,3-oxazole
CAS No.:7065-48-7
Molecular Formula:C22H17ClN2O3S2
Molecular Weight:154.252
Hs Code.:
DSSTox Substance ID:DTXSID10414578
Mol file:7065-48-7.mol

Synonyms:7065-48-7;4-(4-chlorophenyl)sulfonyl-5-(3,4-dihydro-1H-isoquinolin-2-yl)-2-thiophen-2-yl-1,3-oxazole;SCHEMBL23069482;DTXSID10414578;AKOS002776353

Suppliers and Price of 4-(4-chlorophenyl)sulfonyl-5-(3,4-dihydro-1H-isoquinolin-2-yl)-2-thiophen-2-yl-1,3-oxazole

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 4-(4-chlorophenyl)sulfonyl-5-(3,4-dihydro-1H-isoquinolin-2-yl)-2-thiophen-2-yl-1,3-oxazole Edit

Chemical Property:

Vapor Pressure:3.4E-18mmHg at 25°C
Boiling Point:677.2°Cat760mmHg
Flash Point:363.3°C
Density:1.416g/cm³
XLogP3:5.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:456.0369124
Heavy Atom Count:30
Complexity:695

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CC2=CC=CC=C21)C3=C(N=C(O3)C4=CC=CS4)S(=O)(=O)C5=CC=C(C=C5)Cl

Technology Process of 4-(4-chlorophenyl)sulfonyl-5-(3,4-dihydro-1H-isoquinolin-2-yl)-2-thiophen-2-yl-1,3-oxazole

There total 26 articles about 4-(4-chlorophenyl)sulfonyl-5-(3,4-dihydro-1H-isoquinolin-2-yl)-2-thiophen-2-yl-1,3-oxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 3858-47-7
isocarvomenthol

: 7065-48-7
(2S,5R)-(+)-carvomenthone

Guidance literature:: With N-methyl-2-indolinone; tetrapropylammonium perruthennate; 1-ethyl-3-methylimidazolium hexafluorophosphate; In dichloromethane; at 20 ℃; for 2.5h;
DOI:10.1039/b107966m

Reference yield: 53.0%

: 499-75-2
carvacrol

: 499-70-7,3901-91-5,5206-83-7,7065-48-7,13163-73-0,13163-74-1,59471-80-6,116562-19-7,127911-15-3
methyl-2 isopropyl-5 cyclohexanone

Guidance literature:: With C₃₃H₄₉ClNRh; hydrogen; In 2,2,2-trifluoroethanol; water; at 70 ℃; for 24h; under 60006 Torr; Autoclave;
DOI:10.1021/jacs.5b05868