1,4-Diacryloylpiperazine

Base Information

• Chemical Name: 1,4-Diacryloylpiperazine
• CAS No.: 6342-17-2
• Molecular Formula: C10H14N2O2
• Molecular Weight: 194.233
• Hs Code.: 29335995
• NSC Number: 133364,49404
• DSSTox Substance ID: DTXSID10212834
• Nikkaji Number: J674.979H
• Wikidata: Q27216161
• Mol file: 6342-17-2.mol

Synonyms:diacrylylpiperazine

Chemical Property of 1,4-Diacryloylpiperazine

Chemical Property:

• Appearance/Colour: WHITE TO OFF-WHITE POWDER
• Vapor Pressure: 9.73E-08mmHg at 25°C
• Melting Point: 91.5-93.5 °C(lit.)
• Refractive Index: 1.516
• Boiling Point: 434.1 °C at 760 mmHg
• PKA: -0.70±0.70(Predicted)
• Flash Point: 216.5 °C
• PSA: 40.62000
• Density: 1.114 g/cm³
• LogP: -0.09500
• Storage Temp.: 2-8°C
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 194.105527694
• Heavy Atom Count: 14
• Complexity: 237

Purity/Quality:

97% ^*data from raw suppliers

1,4-Diacrylylpiperazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C=CC(=O)N1CCN(CC1)C(=O)C=C
• Uses: Used as a crosslinker in polyacrylamide gels. PIP provides polyacrylamide gels with increased physical strength and improved separation and detection of proteins. 1,4-Diacryloylpiperazine is used as a crosslinker in polyacrylamide gels. PIP provides polyacrylamide gels with increased physical strength and improved separation and detection of proteins Suitable for preparation of gels for PAGE, IEF, 2D electrophoresis and protein sequencing.

Technology Process of 1,4-Diacryloylpiperazine

There total 4 articles about 1,4-Diacryloylpiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

piperazine (110-85-0) + acrylic acid (79-10-7) → 1,4-diacryloylpiperazine (6342-17-2)

Guidance literature:

With (ZrO₂-Fe₃O₄-Nb₂O₅) catalyst; In toluene; at 60 ℃; for 6h; Schlenk technique; Inert atmosphere;

Reference yield: 83.0%

N,N'-bis(morpholinopropionyl)piperazine (32586-73-5) + acetic anhydride (108-24-7) → 4-acetylmorpholine (1696-20-4) + 1,4-diacryloylpiperazine (6342-17-2)

Guidance literature:

N,N'-bis(morpholinopropionyl)piperazine; acetic anhydride; In toluene; at 20 - 80 ℃; for 2h; Inert atmosphere;

With 2,6-di-tert-butyl-4-methyl-phenol; triethylamine; for 12h; Reflux;

Reference yield: 72.0%

piperazine (110-85-0) + acryloyl chloride (814-68-6,25189-84-8) → 1,4-diacryloylpiperazine (6342-17-2)

Guidance literature:

With triethylamine; In dichloromethane; Ambient temperature;

upstream raw materials:

piperazine

acryloyl chloride

N,N'-bis(morpholinopropionyl)piperazine

acetic anhydride

Downstream raw materials:

C₁₄H₂₄N₄O₂

C₁₅H₂₆N₄O₂

G₂-(OH)₈

G₁-(OH)₄