Ethyl 2,6-diaminohexanoate dihydrochloride

Base Information

• Chemical Name: Ethyl 2,6-diaminohexanoate dihydrochloride
• CAS No.: 5721-12-0
• Molecular Formula: C₈H₁₈N₂O₂*2ClH
• Molecular Weight: 247.165
• Hs Code.: 2922498590
• European Community (EC) Number: 227-224-3
• DSSTox Substance ID: DTXSID30972660
• Mol file: 5721-12-0.mol

Synonyms:ethyl 2,6-diaminohexanoate dihydrochloride;5721-12-0;Ethyl DL-lysinate HCl;Ethyl DL-lysinate dihydrochloride;H-Lys-OEt 2 HCl;EINECS 227-224-3;ethyl 2,6-diaminohexanoate;dihydrochloride;SCHEMBL213478;DTXSID30972660;CCG-53506;AKOS024374952;Ethyl lysinate--hydrogen chloride (1/2);FT-0625897;FT-0635034;F86851

Chemical Property of Ethyl 2,6-diaminohexanoate dihydrochloride

Chemical Property:

• Boiling Point: 261.9°Cat760mmHg
• Flash Point: 97.3°C
• PSA: 78.34000
• Density: g/cm³
• LogP: 3.01040
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 246.0901833
• Heavy Atom Count: 14
• Complexity: 128

Purity/Quality:

99% ^*data from raw suppliers

ETHYL-2,6-DIAMINOHEXANOATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi:Irritant
• Statements: R36/37/38:Irritating to eyes, respiratory system and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S37/39:Wear suitable g

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C(CCCCN)N.Cl.Cl

Technology Process of Ethyl 2,6-diaminohexanoate dihydrochloride

There total 3 articles about Ethyl 2,6-diaminohexanoate dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

ethanol (64-17-5) + L-Lysine hydrochloride (657-27-2,10098-89-2,26124-78-7) → L-lysine ethyl ester dihydrochloride (3844-53-9,5721-12-0)

Guidance literature:

With thionyl chloride; Reflux;

DOI:10.1016/j.cclet.2010.11.016

Reference yield:

ethanol (64-17-5) → L-lysine ethyl ester dihydrochloride (3844-53-9,5721-12-0)

Guidance literature:

With hydrogenchloride;

DOI:10.1246/bcsj.11.208

Reference yield:

→ L-lysine ethyl ester dihydrochloride (3844-53-9,5721-12-0)

Guidance literature:

upstream raw materials:

ethanol

L-Lysine hydrochloride

Downstream raw materials:

(5S)-N-(5,9-diamino-7-azanonyl)benzamide

myxochelin A

Refernces

• 1、 Alborzi, Ali Reza,Zahmatkesh, Saeed,Zare, Karim,Sadeghi, Javad. "Optically active: Microwave-assisted synthesis and characterization of l-lysine-derived poly (amide-imide)s". experimental part. p. 485 - 494. Retrieved 2012/04/10.
• 2、 -. "Racemization of an optically active lysine alkyl ester". . . Retrieved 2008/06/13.