N'-(benzenesulfonyl)-3,4,5-trimethoxybenzohydrazide

Base Information

• Chemical Name: N'-(benzenesulfonyl)-3,4,5-trimethoxybenzohydrazide
• CAS No.: 6948-63-6
• Molecular Formula: C16H18N2O6S
• Molecular Weight: 366.395
• NSC Number: 55795
• DSSTox Substance ID: DTXSID60989428
• Wikidata: Q82978522
• Mol file: 6948-63-6.mol

Synonyms:6948-63-6;N'-(benzenesulfonyl)-3,4,5-trimethoxybenzohydrazide;NSC55795;NCIOpen2_007537;DTXSID60989428;NSC-55795;AKOS003421504;N'-(3,4,5-Trimethoxybenzoyl)benzenesulfonohydrazide;N-(Benzenesulfonyl)-3,4,5-trimethoxybenzene-1-carbohydrazonic acid

Chemical Property of N'-(benzenesulfonyl)-3,4,5-trimethoxybenzohydrazide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.307g/cm³
• XLogP3: 2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 7
• Exact Mass: 366.08855747
• Heavy Atom Count: 25
• Complexity: 515

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=CC(=C1OC)OC)C(=O)NNS(=O)(=O)C2=CC=CC=C2

Technology Process of N'-(benzenesulfonyl)-3,4,5-trimethoxybenzohydrazide

There total 2 articles about N'-(benzenesulfonyl)-3,4,5-trimethoxybenzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,4,5-trimethoxybenzoic acid methyl ester (1916-07-0) → N-benzenesulfonyl-N'-(3,4,5-trimethoxy-benzoyl)-hydrazine (6948-63-6)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol; hydrazine hydrate

2: pyridine

With pyridine; methanol; hydrazine hydrate;

DOI:10.1039/jr9440000325

Reference yield:

3,4,5-trimethoxybenzohydrazide (3291-03-0) + benzenesulfonyl chloride (98-09-9) → N-benzenesulfonyl-N'-(3,4,5-trimethoxy-benzoyl)-hydrazine (6948-63-6)

Guidance literature:

With pyridine;

DOI:10.1039/jr9440000325

Reference yield:

N-benzenesulfonyl-N'-(3,4,5-trimethoxy-benzoyl)-hydrazine (6948-63-6) → 3,4,5-trimethoxy-benzaldehyde (86-81-7)

Guidance literature:

With sodium carbonate; ethylene glycol; at 150 - 160 ℃;

DOI:10.1039/jr9440000325

upstream raw materials:

3,4,5-trimethoxybenzohydrazide

benzenesulfonyl chloride

3,4,5-trimethoxybenzoic acid methyl ester

Downstream raw materials:

3,4,5-trimethoxy-benzaldehyde