4'-Chloro-3-(2-pyridyl)acrylophenone

Base Information

Chemical Name:4'-Chloro-3-(2-pyridyl)acrylophenone
CAS No.:5337-52-0
Molecular Formula:C14H10ClNO
Molecular Weight:243.692
Hs Code.:
NSC Number:797
Nikkaji Number:J2.161.743A

Synonyms:NSC797;NSC-797;1-(4-Chlorophenyl)-3-(2-pyridyl)propenal;1-(p-chlorobenzoyl)-2-(4'-pyridyl)-ethene;4'-CHLORO-3-(2-PYRIDYL)ACRYLOPHENONE;5337-52-0

Suppliers and Price of 4'-Chloro-3-(2-pyridyl)acrylophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 4'-Chloro-3-(2-pyridyl)acrylophenone

Chemical Property:

Vapor Pressure:1.22E-06mmHg at 25°C
Boiling Point:400.9°C at 760 mmHg
Flash Point:196.3°C
Density:1.249g/cm³
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:243.0450916
Heavy Atom Count:17
Complexity:282

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=NC(=C1)C=CC(=O)C2=CC=C(C=C2)Cl
Isomeric SMILES:C1=CC=NC(=C1)/C=C/C(=O)C2=CC=C(C=C2)Cl

Technology Process of 4'-Chloro-3-(2-pyridyl)acrylophenone

There total 2 articles about 4'-Chloro-3-(2-pyridyl)acrylophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1121-60-4
pyridine-2-carbaldehyde

: 99-91-2
para-chloroacetophenone

: 5337-52-0
(E)-1-(4-chlorophenyl)-3-(pyridin-2-yl)prop-2-en-1-one

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at 25 ℃; for 36h;
DOI:10.1002/adsc.200404318

Reference yield:

: 5337-52-0
(E)-1-(4-chlorophenyl)-3-(pyridin-2-yl)prop-2-en-1-one

Guidance literature:: Picolinaldehyd, p-Cl-C6H4-COCH3, Piperidin, w. Eg.;
DOI:10.1002/jps.2600561029

Reference yield: 86.0%

: 50-01-1
guanidine hydrochloride

: 5337-52-0
(E)-1-(4-chlorophenyl)-3-(pyridin-2-yl)prop-2-en-1-one

: 1091617-17-2
4-(4-chlorophenyl)-6-(pyridin-2-yl)pyrimidin-2-amine

Guidance literature:: With potassium hydroxide; In ethanol; at 25 - 30 ℃; for 0.333333h; Temperature; Sonication; Green chemistry;
DOI:10.1007/s11164-018-3292-5