N-Formyl-2-phenylalanine

Base Information

• Chemical Name: N-Formyl-2-phenylalanine
• CAS No.: 3381-60-0
• Molecular Formula: C10H11NO3
• Molecular Weight: 193.1992
• NSC Number: 152660,152659,133921
• Nikkaji Number: J1.405.919I
• Mol file: 3381-60-0.mol

Synonyms:3381-60-0;N-Formyl-2-phenylalanine;NSC152659;SCHEMBL1455027;NSC133921;NSC152660;2-formylamino-2-phenyl-propionic acid;AKOS005068096;(+)-N-FORMYL-2-PHENYLALANINE;NSC-133921;NSC-152659;NSC-152660;(RS)-2-Formamido-2-phenylpropanoic acid;33228-58-9

Chemical Property of N-Formyl-2-phenylalanine

Chemical Property:

• Vapor Pressure: 2.55E-08mmHg at 25°C
• Boiling Point: 434.5°Cat760mmHg
• Flash Point: 216.6°C
• Density: 1.231g/cm³
• XLogP3: 1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 193.07389321
• Heavy Atom Count: 14
• Complexity: 223

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C1=CC=CC=C1)(C(=O)O)NC=O

Technology Process of N-Formyl-2-phenylalanine

There total 3 articles about N-Formyl-2-phenylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formic acid (64-18-6) + 2-amino-2-phenylpropanoic acid (565-07-1,6945-32-0) → 2-formylamino-2-phenyl-propionic acid (3381-60-0)

Guidance literature:

Reference yield:

formic acid (64-18-6) + 2-Azido-2-phenyl-propionic acid; compound with dicyclohexyl-amine → 2-formylamino-2-phenyl-propionic acid (3381-60-0)

Guidance literature:

Multistep reaction; (i) H₂, Pd-CaCO₃, (ii) /BRN= 1209246/;

Reference yield:

→ 2-formylamino-2-phenyl-propionic acid (3381-60-0)

Guidance literature:

2-Amino-2-phenyl-propionsaeure 1. Ameisensaeure, 60grad, 15 min 2. Acetanhydrid, 60-62grad;

DOI:10.1021/ja01470a033

upstream raw materials:

formic acid

2-amino-2-phenylpropanoic acid

Downstream raw materials:

methyl rac-2-benzyl-2-formamidopropionat

(S)-2-formylamino-2-phenyl-propionic acid