7-Methyl-1H-indene

Base Information

• Chemical Name: 7-Methyl-1H-indene
• CAS No.: 7372-92-1
• Molecular Formula: C10H10
• Molecular Weight: 130.189
• European Community (EC) Number: 230-929-9
• DSSTox Substance ID: DTXSID50224032
• Nikkaji Number: J212.373H
• Wikidata: Q83102542
• Mol file: 7372-92-1.mol

Synonyms:7-Methyl-1H-indene;7372-92-1;Indene, 7-methyl-;EINECS 230-929-9;1H-Indene, 7-methyl-;7-methylindene;DTXSID50224032;MFCD18064751;AKOS024463977;Y10332;EN300-1613355

Chemical Property of 7-Methyl-1H-indene

Chemical Property:

• Vapor Pressure: 0.259mmHg at 25°C
• Melting Point: 80°C (estimate)
• Refractive Index: 1.5680
• Boiling Point: 211.9°Cat760mmHg
• Flash Point: 74.9°C
• PSA: 0.00000
• Density: 1.016g/cm³
• LogP: 2.56430
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 130.078250319
• Heavy Atom Count: 10
• Complexity: 146

Purity/Quality:

97% ^*data from raw suppliers

7-Methyl-1H-indene 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C2CC=CC2=CC=C1

Technology Process of 7-Methyl-1H-indene

There total 13 articles about 7-Methyl-1H-indene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

4-bromo-3H-indene (16657-07-1) + methylmagnesium bromide (75-16-1) → 7-methyl-1H-indene (7372-92-1)

Guidance literature:

With [nickel(II)dichloride(1,3-bis(diphenylphosphino)propane)]; In diethyl ether; for 22h; Heating;

DOI:10.1021/jo00196a024

Reference yield: 80.0%

4-methyl-2,3-dihydro-1H-inden-1-ol (67864-03-3) → 7-methyl-1H-indene (7372-92-1)

Guidance literature:

With toluene-4-sulfonic acid; In benzene; for 3h; Heating;

Reference yield: 78.0%

(E)-3-methyl-2-(3-(o-tolyl)allyl)benzaldehyde → 7-methyl-1H-indene (7372-92-1)

Guidance literature:

With 4-phenylphenyl-diphenylmethylium tetrafluoroborate; In dichloromethane; at 20 ℃; for 0.5h; Schlenk technique; Inert atmosphere;

DOI:10.1039/C8CC06734A

upstream raw materials:

4-bromo-3H-indene

methylmagnesium bromide

4-methyl-2,3-dihydro-1H-inden-1-ol

4-methylindanone

Downstream raw materials:

5-methylisoquinoline

2,3-dihydro-4-methyl-1H-indene

3-methyl-2-(2-oxoethyl)benzaldehyde