2-Methylacridine

Base Information

• Chemical Name: 2-Methylacridine
• CAS No.: 613-15-0
• Molecular Formula: C14H11N
• Molecular Weight: 193.248
• European Community (EC) Number: 210-331-4
• NSC Number: 6143
• UNII: V6R4PDB5HV
• DSSTox Substance ID: DTXSID10210193
• Nikkaji Number: J96.110H
• Wikidata: Q27291603
• Mol file: 613-15-0.mol

Synonyms:2-Methylacridine;613-15-0;ACRIDINE, 2-METHYL-;NSC 6143;EINECS 210-331-4;UNII-V6R4PDB5HV;V6R4PDB5HV;BRN 0133145;NSC-6143;5-20-08-00251 (Beilstein Handbook Reference);NSC6143;METHYLACRIDINE, 2-;SCHEMBL4427125;DTXSID10210193;AKOS006274735;Q27291603

Chemical Property of 2-Methylacridine

Chemical Property:

• Vapor Pressure: 4.19E-05mmHg at 25°C
• Boiling Point: 361.9°Cat760mmHg
• Flash Point: 160°C
• PSA: 12.89000
• Density: 1.155g/cm³
• LogP: 3.69640
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 193.089149355
• Heavy Atom Count: 15
• Complexity: 225

Purity/Quality:

98%min ^*data from raw suppliers

2-METHYLACRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC2=CC3=CC=CC=C3N=C2C=C1

Technology Process of 2-Methylacridine

There total 51 articles about 2-Methylacridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

bis(4-methylphenyl)iodonium trifluoromethanesulfonate (123726-16-9) + o-aminobenzaldehyde (529-23-7) → 2-methylacridine (613-15-0)

Guidance literature:

With copper(l) iodide; In 1,2-dichloro-ethane; at 65 ℃; for 12h; Temperature; Inert atmosphere; Sealed tube;

DOI:10.1002/ejoc.201500161

Reference yield: 84.0%

m-tolyl aldehyde (620-23-5) + Phenyl azide (622-37-7) → 2-methylacridine (613-15-0)

Guidance literature:

With silver hexafluoroantimonate; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; benzylamine; at 120 ℃; for 16h; Inert atmosphere; Glovebox; Schlenk technique; Sealed tube;

DOI:10.1080/00397911.2018.1448418

Reference yield: 83.0%

2-(4-methylphenylamino)benzaldehyde (62152-50-5) → 2-methylacridine (613-15-0)

Guidance literature:

In trifluoroacetic acid; for 30h; Ambient temperature;

upstream raw materials:

2-methyl-9,10-dihydroacridine

2-methyl-10H-acridin-9-one

2-methyl-1,2,3,4-tetrahydroacridine

bis-(2-amino-5-methyl-phenyl)-phenyl-methane

Downstream raw materials:

N'-(3-acridinylmethylidene)-4-dimethylaminoaniline N'-oxide