2-Methylbutan-2-amine

Base Information

• Chemical Name: 2-Methylbutan-2-amine
• CAS No.: 594-39-8
• Molecular Formula: C5H13N
• Molecular Weight: 87.1649
• Hs Code.: 29211999
• European Community (EC) Number: 209-839-9
• DSSTox Substance ID: DTXSID5060485
• Nikkaji Number: J6.774A
• Wikidata: Q15632841
• Mol file: 594-39-8.mol

Synonyms:tert-Amylamine;2-methylbutan-2-amine;594-39-8;tert-Pentylamine;2-Butanamine, 2-methyl-;t-Amylamine;1,1-Dimethylpropylamine;2-Methyl-2-butylamine;2-Amino-2-methylbutane;1,1-dimethyl-propylamine;1,1-dimethyl-1-propylamine;EINECS 209-839-9;2-Methyl-Butan-2-Amine;1,1-dimethyl-n-propylamine;t-pentylamine;tert amylamine;tert-amyl amine;tertiaryamylamine;tert-pentyl amine;tert-pentyl-amine;tert.-pentylamine;tertiary-pentylamine;2-methyl-2-butanamine;tert-Amylamine, 98%;tert-C5H11NH2;2-Methyl-2-aminobutane;DTXSID5060485;CHEBI:84236;GELMWIVBBPAMIO-UHFFFAOYSA-;STR00931;.alpha.,.alpha.-Dimethylpropylamine;MFCD00008056;AKOS000120304;A1002;FT-0632473;EN300-20706;Q15632841;F8889-6104;Z104480062

Chemical Property of 2-Methylbutan-2-amine

Chemical Property:

• Appearance/Colour: clear colorless liquid
• Vapor Pressure: 98.5mmHg at 25°C
• Melting Point: -105°C
• Refractive Index: n20/D 1.3996(lit.)
• Boiling Point: 77 °C at 760 mmHg
• PKA: 10.85(at 19℃)
• Flash Point: 30 °F
• PSA: 26.02000
• Density: 0.759 g/cm³
• LogP: 1.83400
• Storage Temp.: Flammables area
• Water Solubility.: Soluble in water
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 87.104799419
• Heavy Atom Count: 6
• Complexity: 39.2

Purity/Quality:

98%,99%, ^*data from raw suppliers

tert-Amylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,C,T
• Hazard Codes: F,C,T
• Statements: 11-34-25
• Safety Statements: 16-26-27-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCC(C)(C)N
• Uses: tert-Amylamine was used as a substitute for t-butylamino substituent in cyanobenzylamine derivative.

Technology Process of 2-Methylbutan-2-amine

There total 25 articles about 2-Methylbutan-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

tert-amylurea (625-15-0) → 2-methyl-2-butylamine (594-39-8)

Guidance literature:

With calcium hydroxide; at 240 - 270 ℃; for 1.5h;

Reference yield:

tert-Amyl alcohol (75-85-4) → 2-methyl-2-butylamine (594-39-8)

Guidance literature:

tert-Amyl alcohol; With trimethylsilylazide; boron trifluoride diethyl etherate; In benzene; for 24h;

With sodium hydrogencarbonate; In benzene; for 0.5h;

With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 1.5h; under 2327.17 Torr;

DOI:10.1021/jm0600085

Reference yield:

1,1-dimethylprop-3-ynylamine (2978-58-7) → 2-methyl-2-butylamine (594-39-8)

Guidance literature:

With hydrogen; nickel; In ethanol;

DOI:10.1021/jo01019a033

upstream raw materials:

O-Methylhydroxylamin

1,1-dimethylpropylmagnesium chloride

tert-Amyl alcohol

sodium cyanide

Downstream raw materials:

benzothiazole-2-sulfenic acid tert-pentylamide

2-methyl-2-nitrosobutane

1,1-dimethylpropyl isothiocyanate

2-methyl-2-nitrobutane