malonic-n,n’-dicyclohexyldiamide

Base Information

• Chemical Name: malonic-n,n’-dicyclohexyldiamide
• CAS No.: 10256-00-5
• Molecular Formula: C15H26 N2 O2
• Molecular Weight: 266.384
• Hs Code.: 2924299090
• Mol file: 10256-00-5.mol

Synonyms:Malonamide,N,N'-dicyclohexyl- (6CI,7CI,8CI); Propanediamide, N,N'-dicyclohexyl- (9CI);Malonic N,N'-dicyclohexyldiamide; Malonyl N,N'-dicyclohexyldiamide;N,N'-Dicyclohexylmalonamide

Chemical Property of malonic-n,n’-dicyclohexyldiamide

Chemical Property:

• Vapor Pressure: 3.25E-11mmHg at 25°C
• Boiling Point: 557.8°Cat760mmHg
• Flash Point: 229.9°C
• PSA: 58.20000
• Density: 1.271g/cm³
• LogP: 3.05610

Purity/Quality:

98%,99%, ^*data from raw suppliers

N,N''-Dicyclohexylpropanediamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of malonic-n,n’-dicyclohexyldiamide

There total 9 articles about malonic-n,n’-dicyclohexyldiamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

Acetyl-N,N'-dicyclohexylmalonamide (73453-46-0) → N,N'-dicyclohexyl-malonamide (10256-00-5)

Guidance literature:

In ethanol; for 0.5h; Heating;

DOI:10.1021/jo01300a036

Reference yield: 21.0%

Ethyl Acetyl-N-cyclohexylmalonamate (73453-43-7) → N-cyclohexylacetamide (1124-53-4) + N,N'-dicyclohexyl-malonamide (10256-00-5) + n-Hexyl acetyl-N-cyclohexylmalonamate (73453-44-8) + Acetyl-N,N'-dicyclohexylmalonamide (73453-46-0)

Guidance literature:

With hexan-1-ol; for 0.333333h; Further byproducts given; Heating;

DOI:10.1021/jo01300a036

Reference yield:

Ethyl Acetyl-N-cyclohexylmalonamate (73453-43-7) + hexan-1-ol (111-27-3) → N-cyclohexylacetamide (1124-53-4) + N,N'-dicyclohexyl-malonamide (10256-00-5) + n-Hexyl acetyl-N-cyclohexylmalonamate (73453-44-8) + Acetyl-N,N'-dicyclohexylmalonamide (73453-46-0)

Guidance literature:

for 0.333333h; Further byproducts given; Heating;

DOI:10.1021/jo01300a036

upstream raw materials:

malonyldiurethane

cyclohexylamine

diethyl malonate

Acetyl-N,N'-dicyclohexylmalonamide

Downstream raw materials:

1,1,3,3-Tetrakis-cyclohexylcarbamoyl-propan

1-cyclohexyl-2,4,5-trioxo-pyrrolidine-3-carboxylic acid cyclohexylamide

Refernces

• 1、 Wicks, Zeno W.,Wu, Kuang-Jong. "Reactions of Acetoacetic Ester Blocked Cyclohexyl Isocyanate". . p. 2446 - 2448. Retrieved 2007/10/02.
• 2、 BRAEUNIGER,STENS. "TRANSFORMATION OF MALONIC ACID DIAMIDE DERIVATIVES UNDER CONDITIONS OF". . p. 585 - 600. Retrieved 2007/10/05.