Technology Process of 1-(2-Indanyl)pyrrolidine
There total 6 articles about 1-(2-Indanyl)pyrrolidine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
diphenyl(2',4',6'-triisopropyl-3,6-dimethoxybiphenyl-2-yl)phosphine; palladium diacetate; lithium tert-butoxide;
at 95 ℃;
for 16h;
Reagent/catalyst;
Temperature;
Catalytic behavior;
Inert atmosphere;
Schlenk technique;
DOI:10.1021/jacs.5b07203
- Guidance literature:
-
With
sodium cyanoborohydride; acetic acid;
In
methanol;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium carbonate / acetone / 14 h / 65 °C / Inert atmosphere
2: N,N-dimethyl-formamide / 16 h / 200 °C / Inert atmosphere; Autoclave
3: pyridine / dichloromethane / 0 - 20 °C / Inert atmosphere
4: palladium diacetate; lithium tert-butoxide; diphenyl(2',4',6'-triisopropyl-3,6-dimethoxybiphenyl-2-yl)phosphine / 16 h / 95 °C / Inert atmosphere; Schlenk technique
With
pyridine; diphenyl(2',4',6'-triisopropyl-3,6-dimethoxybiphenyl-2-yl)phosphine; palladium diacetate; potassium carbonate; lithium tert-butoxide;
In
dichloromethane; N,N-dimethyl-formamide; acetone;
DOI:10.1021/jacs.5b07203
