Benzamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-4-methyl-5-((methylamino)sulfonylamino)-

Base Information

Chemical Name:Benzamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-4-methyl-5-((methylamino)sulfonylamino)-
CAS No.:68256-24-6
Molecular Formula:C17H28N4O4S
Molecular Weight:384.4936
Hs Code.:
DSSTox Substance ID:DTXSID00987781
ChEMBL ID:CHEMBL14314

Synonyms:BRN 0452015;68256-24-6;Benzamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-4-methyl-5-((methylamino)sulfonylamino)-;CHEMBL14314;SCHEMBL11238878;DTXSID00987781;LS-26834;N-[(1-Ethylpyrrolidin-2-yl)methyl]-2-methoxy-4-methyl-5-[(methylsulfamoyl)amino]benzene-1-carboximidic acid

Suppliers and Price of Benzamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-4-methyl-5-((methylamino)sulfonylamino)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-4-methyl-5-((methylamino)sulfonylamino)-

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.229g/cm³
XLogP3:1.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:8
Exact Mass:384.18312656
Heavy Atom Count:26
Complexity:566

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1CCCC1CNC(=O)C2=C(C=C(C(=C2)NS(=O)(=O)NC)C)OC

Technology Process of Benzamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-4-methyl-5-((methylamino)sulfonylamino)-

There total 6 articles about Benzamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-4-methyl-5-((methylamino)sulfonylamino)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 10438-96-7
N-methylsulfamoyl chloride

: 68255-94-7
N-(1-ethyl-2-pyrrolidinylmethyl)-2-methoxy-4-methyl-5-aminobenzamide

: 68256-24-6
N-(1-ethyl-2-pyrrolidinylmethyl)-2-methoxy-4-methyl-5-methylaminosulfonamidobenzamide

Guidance literature:: With triethylamine; In dichloromethane; for 0.25h;
DOI:10.1021/jm00375a009

Reference yield:

: 26116-12-1
1-ethyl-2-pyrrolidinemethanamine

: 68256-24-6
N-(1-ethyl-2-pyrrolidinylmethyl)-2-methoxy-4-methyl-5-methylaminosulfonamidobenzamide

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N / CH₂Cl₂ / 0.25 h / Ambient temperature

2: 51 percent / Sn, HCl aq. / 4 h / 50 °C

3: 51 percent / Et₃N / CH₂Cl₂ / 0.25 h

With hydrogenchloride; tin; triethylamine; In dichloromethane;
DOI:10.1021/jm00375a009

Reference yield:

: 90763-12-5
2-methoxy-4-methyl-5-nitrobenzoic acid

: 68256-24-6
N-(1-ethyl-2-pyrrolidinylmethyl)-2-methoxy-4-methyl-5-methylaminosulfonamidobenzamide

Guidance literature:: Multi-step reaction with 4 steps

1: SOCl₂ / 1 h / Heating

2: Et₃N / CH₂Cl₂ / 0.25 h / Ambient temperature

3: 51 percent / Sn, HCl aq. / 4 h / 50 °C

4: 51 percent / Et₃N / CH₂Cl₂ / 0.25 h

With hydrogenchloride; tin; thionyl chloride; triethylamine; In dichloromethane;
DOI:10.1021/jm00375a009