4-Methoxy-3-methylbenzaldehyde

Base Information

• Chemical Name: 4-Methoxy-3-methylbenzaldehyde
• CAS No.: 32723-67-4
• Molecular Formula: C9H10O2
• Molecular Weight: 150.177
• Hs Code.: 29124990
• European Community (EC) Number: 251-177-8
• UNII: UH5G8E8NAN
• DSSTox Substance ID: DTXSID60186399
• Nikkaji Number: J149.918A
• Wikidata: Q72487532
• Mol file: 32723-67-4.mol

Synonyms:4-Methoxy-3-methylbenzaldehyde;32723-67-4;3-Methyl-p-anisaldehyde;3-Methyl-4-anisaldehyde;3-methyl-4-methoxybenzaldehyde;Benzaldehyde, 4-methoxy-3-methyl-;4-Methoxy-3-methyl-benzaldehyde;3-Methyl p-anisaldehyde;MFCD00003375;UH5G8E8NAN;3-Methyl-para-anisaldehyde;EINECS 251-177-8;4-METHOXY-M-TOLUALDEHYDE;3-methylanisaldehyde;UNII-UH5G8E8NAN;p-Anisaldehyde, 3-methyl-;SCHEMBL493442;3-Methyl-4-methoxy-benzaldehyd;MYLBIQHZWFWSMH-UHFFFAOYSA-;DTXSID60186399;4-Methoxy-3-methylbenzaldehyde #;CL8365;GEO-01749;4-Methoxy-3-methylbenzaldehyde, 99%;AKOS000113558;(4-Methoxy-3-methylphenyl)formaldehyde;CS-W008750;GS-3209;4-METHOXY-3-METHYLBENZYLALDEHYDE;BP-10265;SY020960;A5849;AM20060379;BB 0259240;FT-0618890;EN300-24724;3-Methyl-p-anisaldehyde, purum, >=98.0% (GC);W-106826;Z199532230

Chemical Property of 4-Methoxy-3-methylbenzaldehyde

Chemical Property:

• Appearance/Colour: Clear pale yellow to green liquid
• Vapor Pressure: 0.0142mmHg at 25°C
• Refractive Index: n20/D 1.569
• Boiling Point: 257.8 °C at 760 mmHg
• Flash Point: 112.2 °C
• PSA: 26.30000
• Density: 1.062 g/cm³
• LogP: 1.81610
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility.: Chloroform, Ethyl Acetate
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 150.068079557
• Heavy Atom Count: 11
• Complexity: 134

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Methoxy-3-methylbenzaldehyde ^*data from reagent suppliers

Safty Information:

• Safety Statements: 23-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=C(C=CC(=C1)C=O)OC
• Uses: 4-Methoxy-3-methylbenzaldehyde was used in the preparation of (4-methoxy-3-methylphenyl)-2-nitroalkene.

Technology Process of 4-Methoxy-3-methylbenzaldehyde

There total 19 articles about 4-Methoxy-3-methylbenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3,4-dimethylanisole (4685-47-6) → 3-methyl-4-anisaldehyde (32723-67-4)

Guidance literature:

With dipotassium peroxodisulfate; copper(II) sulfate; In water; acetonitrile; for 0.5h; Heating / reflux;

Reference yield: 93.0%

sodium; hydroxy-(4-methoxy-3-methyl-phenyl)-methanesulfonate → 3-methyl-4-anisaldehyde (32723-67-4)

Guidance literature:

With ammonium acetate; for 0.00166667h; microwave irradiation;

Reference yield: 85.0%

2-methylmethoxybenzene (578-58-5) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 3-methyl-4-anisaldehyde (32723-67-4)

Guidance literature:

N,N-dimethyl-formamide; With trichlorophosphate; for 0.25h; cooling;

2-methylmethoxybenzene; In N,N-dimethyl-formamide; at 100 - 110 ℃;

DOI:10.1016/j.tet.2006.09.056

upstream raw materials:

hydrogen cyanide

2-methylmethoxybenzene

4-ethyl-2-methylphenyl methyl ether

bis-(4-methoxy-3-methyl-benzyl)-ether

Downstream raw materials:

α-benzoylamino-4-methoxy-3-methyl-cinnamic acid

4-methoxy-3-methyl-mandelonitrile

4-Methyl-1-<4-methoxy-3-methyl-phenyl>-penten-(1)-on-(3)

4-(4-methoxy-3-methyl-benzylidene)-2-phenyl-4H-oxazol-5-one

Refernces

• 1、 Ivanova, Lena V.,Navale, Tushar S.,Wang, Denan,Lindeman, Sergey,Ivanov, Maxim V.,Rathore, Rajendra. "Towards the rational design of novel charge-transfer materials: Biaryls with a dihedral angle-independent hole delocalization mechanism". supporting information. p. 5851 - 5854. Retrieved 2018/06/13.
• 2、 Chandrasekhar,Reddy, N. Ramakrishna,Rao, Y. Srinivasa. "Synthetic studies on Ecteinascidin-743: synthesis of building blocks through Sharpless asymmetric dihydroxylation and aza-Michael reactions". . p. 12098 - 12107. Retrieved 2007/10/03.