4-ethyl-2-methylphenyl methyl ether

Base Information

• Chemical Name: 4-ethyl-2-methylphenyl methyl ether
• CAS No.: 21573-35-3
• Molecular Formula: C₁₀H₁₄O
• Molecular Weight: 150.221
• Mol file: 21573-35-3.mol

Synonyms:4-ethyl-2-methylphenyl methyl ether

Chemical Property of 4-ethyl-2-methylphenyl methyl ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-ethyl-2-methylphenyl methyl ether

There total 7 articles about 4-ethyl-2-methylphenyl methyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-cresol (106-44-5) + dimethyl sulfate (77-78-1) → p-methylanizole (104-93-8) + 2,4-dimethylanisole (6738-23-4) + 4-ethyl-2-methylphenyl methyl ether (21573-35-3) + p-ethylanisole (1515-95-3)

Guidance literature:

With n-butyllithium; potassium tert-butylate; Yield given. Multistep reaction. Yields of byproduct given; 1.) heptane, hexane, reflux, 20 h, 2.) THF;

DOI:10.1021/jo00359a010

Reference yield:

dimethyl sulfate (77-78-1) + 2,4-Xylenol (105-67-9) → 2,4-dimethylanisole (6738-23-4) + 2-ethyl-4-methylphenyl methyl ether (79744-78-8) + 4-ethyl-2-methylphenyl methyl ether (21573-35-3) + 2,4-diethylanisole (110457-64-2)

Guidance literature:

With n-butyllithium; potassium tert-butylate; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given; 1.) heptane, hexane, reflux, 18 h, 2.) THF, 0 deg C, 18 h;

DOI:10.1021/jo00229a032

Reference yield:

dimethyl sulfate (77-78-1) + 2,4-Xylenol (105-67-9) → 2,4-dimethylanisole (6738-23-4) + 2-ethyl-4-methylphenyl methyl ether (79744-78-8) + 4-ethyl-2-methylphenyl methyl ether (21573-35-3) + 5-ethyl-2-methoxy-1,3-dimethylbenzene (110457-67-5)

Guidance literature:

With n-butyllithium; potassium tert-butylate; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given; 1.) heptane, hexane, reflux, 18 h, 2.) THF, 0 deg C, 18 h;

DOI:10.1021/jo00229a032

upstream raw materials:

p-cresol

dimethyl sulfate

4-ethyl-2-methylphenol

2,4-Xylenol

Downstream raw materials:

3-methyl-4-anisaldehyde

5-ethyl-2-hydroxy-3-methyl-benzaldehyde

Refernces

• 1、 Bates, Robert B.,Siahaan, Teruna J.. "Preparation and Reactions of Dianions from the Cresols". . p. 1432 - 1434. Retrieved 2007/10/02.