3-(2-Hydroxyethoxy)benzoic acid

Base Information

Chemical Name:3-(2-Hydroxyethoxy)benzoic acid
CAS No.:25781-99-1
Molecular Formula:C9H10 O4
Molecular Weight:182.176
Hs Code.:2918990090
European Community (EC) Number:696-520-6
NSC Number:137280
DSSTox Substance ID:DTXSID30300500
Nikkaji Number:J1.195.766H
Wikidata:Q82043593
ChEMBL ID:CHEMBL1741575
Mol file:25781-99-1.mol

Synonyms:3-(2-hydroxyethoxy)benzoic acid;25781-99-1;3-(2-Hydroxy-ethoxy)-benzoic acid;NSC137280;NSC-137280;NCIStruc1_000208;NCIStruc2_000060;3-(2-hydroxyethoxy)benzoicacid;SCHEMBL8517907;CHEMBL1741575;DTXSID30300500;CCG-37968;MFCD06203193;NCGC00014355;NCI137280;AKOS000191312;NSC 137280;NCGC00014355-02;NCGC00097464-01;BS-27934;NCI60_000846;CS-0359458;EN300-7366005

Suppliers and Price of 3-(2-Hydroxyethoxy)benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-(2-Hydroxyethoxy)benzoicacid 95+%
5g
$ 752.00

American Custom Chemicals Corporation
3-(2-HYDROXY-ETHOXY)-BENZOIC ACID 95.00%
5MG
$ 499.14

Alichem
3-(2-Hydroxyethoxy)benzoicacid
5g
$ 805.60

Total 7 raw suppliers

Chemical Property of 3-(2-Hydroxyethoxy)benzoic acid

Chemical Property:

Vapor Pressure:1.04E-06mmHg at 25°C
Boiling Point:387.9°Cat760mmHg
Flash Point:160.6°C
PSA：66.76000
Density:1.301g/cm³
LogP:0.75590
XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:182.05790880
Heavy Atom Count:13
Complexity:169

Purity/Quality:

99% ^*data from raw suppliers

3-(2-Hydroxyethoxy)benzoicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)OCCO)C(=O)O

Technology Process of 3-(2-Hydroxyethoxy)benzoic acid

There total 2 articles about 3-(2-Hydroxyethoxy)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 124-38-9,18923-20-1
carbon dioxide

: 6161-83-7
2-(3-chlorophenoxy)ethanol

: 25781-99-1
3-(2-hydroxyethoxy)benzoic acid

Guidance literature:: 2-(3-chlorophenoxy)ethanol; With n-butyllithium; magnesium(2-ethoxyethylate)2; In tetrahydrofuran; at -78 ℃; for 0.25h;

With lithium dihydronaphthylide radical; In tetrahydrofuran; at -78 - -50 ℃; for 0.333333h;

carbon dioxide; In tetrahydrofuran; diethyl ether;
DOI:10.1016/S0022-328X(99)00425-8

Reference yield:

: 42772-85-0
2-hydroxyethyl 4-methylbenzenesulfonate

: 99-06-9
3-Carboxyphenol

: 25781-99-1
3-(2-hydroxyethoxy)benzoic acid

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 5h;
DOI:10.1080/14756366.2019.1690481

Reference yield: 85.0%

: 1267986-38-8
4-Chlorodeacetylcolchicine

: 25781-99-1
3-(2-hydroxyethoxy)benzoic acid

: 4-chloro-N-[3-(2-hydroxyethoxy)benzoyl]deacetyl colchicine

Guidance literature:: 3-(2-hydroxyethoxy)benzoic acid; With 1-hydroxybenzotriazol-hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 0.5h; Inert atmosphere;

4-Chlorodeacetylcolchicine; In dichloromethane; at 20 ℃;