[1-(4'-Bromobiphenyl-4-yl)-2-phenylethyl]malonic acid

Base Information

Chemical Name:[1-(4'-Bromobiphenyl-4-yl)-2-phenylethyl]malonic acid
CAS No.:60313-47-5
Molecular Formula:C23H19 Br O4
Molecular Weight:439.305
Hs Code.:
European Community (EC) Number:262-165-7
DSSTox Substance ID:DTXSID40975723
Nikkaji Number:J298.830E
Mol file:60313-47-5.mol

Synonyms:60313-47-5;[1-(4'-bromobiphenyl-4-yl)-2-phenylethyl]malonic acid;EINECS 262-165-7;(1-(4'-Bromo(1,1'-biphenyl)-4-yl)-2-phenylethyl)malonic acid;[1-(4'-bromo[1,1'-biphenyl]-4-yl)-2-phenylethyl]malonic acid;[1-(4'-Bromo[1,1'-biphenyl]-4-yl)-2-phenylethyl]propanedioic acid;[1-[4'-Bromo[1,1'-biphenyl]-4-yl]-2-phenylethyl]propanedioic acid;C23H19BrO4;C23-H19-Br-O4;DTXSID40975723

Suppliers and Price of [1-(4'-Bromobiphenyl-4-yl)-2-phenylethyl]malonic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of [1-(4'-Bromobiphenyl-4-yl)-2-phenylethyl]malonic acid

Chemical Property:

PSA：74.60000
LogP:5.22780
XLogP3:5.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:438.04667
Heavy Atom Count:28
Complexity:501

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)C(C(=O)O)C(=O)O

Technology Process of [1-(4'-Bromobiphenyl-4-yl)-2-phenylethyl]malonic acid

There total 5 articles about [1-(4'-Bromobiphenyl-4-yl)-2-phenylethyl]malonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 92-66-0
4-bromo-1,1'-biphenyl

: 60313-47-5
{1-[4'-bromo(1,1'-biphenyl)-4-yl]-2-phenylethyl}malonic acid

Guidance literature:: Multi-step reaction with 4 steps

1: AlCl₃

2: NaBH₄

3: PBr₃

4: (i) NaH, DMF, (ii) /BRN= 2280728/, (iii) aq. NaOH, EtOH

With sodium tetrahydroborate; aluminium trichloride; phosphorus tribromide;
DOI:10.1039/P19760001190

Reference yield:

: 60313-17-9
4'-bromo-α-(phenylmethyl)(1,1'-biphenyl)-4-methanol

: 60313-47-5
{1-[4'-bromo(1,1'-biphenyl)-4-yl]-2-phenylethyl}malonic acid

Guidance literature:: Multi-step reaction with 2 steps

1: PBr₃

2: (i) NaH, DMF, (ii) /BRN= 2280728/, (iii) aq. NaOH, EtOH

With phosphorus tribromide;
DOI:10.1039/P19760001190

Reference yield:

: 60312-95-0
1-[4'-bromo(1,1'-biphenyl)-4-yl]-2-phenylethan-1-one

: 60313-47-5
{1-[4'-bromo(1,1'-biphenyl)-4-yl]-2-phenylethyl}malonic acid

Guidance literature:: Multi-step reaction with 3 steps

1: NaBH₄

2: PBr₃

3: (i) NaH, DMF, (ii) /BRN= 2280728/, (iii) aq. NaOH, EtOH

With sodium tetrahydroborate; phosphorus tribromide;
DOI:10.1039/P19760001190