4'-Bromo-alpha-(phenylmethyl)[1,1'-biphenyl]-4-methanol

Base Information

• Chemical Name: 4'-Bromo-alpha-(phenylmethyl)[1,1'-biphenyl]-4-methanol
• CAS No.: 60313-17-9
• Molecular Formula: C20H17 Br O
• Molecular Weight: 353.258
• Hs Code.: 2906299090
• European Community (EC) Number: 262-163-6
• DSSTox Substance ID: DTXSID20975721
• Nikkaji Number: J298.828C
• Mol file: 60313-17-9.mol

Synonyms:60313-17-9;4'-Bromo-alpha-(phenylmethyl)[1,1'-biphenyl]-4-methanol;1-[4-(4-bromophenyl)phenyl]-2-phenylethanol;EINECS 262-163-6;4'-Bromo-alpha-(phenylmethyl)(1,1'-biphenyl)-4-methanol;C20H17BrO;C20-H17-Br-O;DTXSID20975721;1-(4'-Bromo[1,1'-biphenyl]-4-yl)-2-phenylethan-1-ol

Chemical Property of 4'-Bromo-alpha-(phenylmethyl)[1,1'-biphenyl]-4-methanol

Chemical Property:

• Boiling Point: 466.1oC at 760 mmHg
• Flash Point: 235.7oC
• PSA: 20.23000
• Density: 1.344g/cm3
• LogP: 5.39220
• XLogP3: 5.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 352.04628
• Heavy Atom Count: 22
• Complexity: 310

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O

Technology Process of 4'-Bromo-alpha-(phenylmethyl)[1,1'-biphenyl]-4-methanol

There total 3 articles about 4'-Bromo-alpha-(phenylmethyl)[1,1'-biphenyl]-4-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-[4'-bromo(1,1'-biphenyl)-4-yl]-2-phenylethan-1-one (60312-95-0) → 4'-bromo-α-(phenylmethyl)(1,1'-biphenyl)-4-methanol (60313-17-9)

Guidance literature:

With sodium tetrahydroborate;

DOI:10.1039/P19760001190

Reference yield:

4-bromo-1,1'-biphenyl (92-66-0) → 4'-bromo-α-(phenylmethyl)(1,1'-biphenyl)-4-methanol (60313-17-9)

Guidance literature:

Multi-step reaction with 2 steps

1: AlCl₃

2: NaBH₄

With sodium tetrahydroborate; aluminium trichloride;

DOI:10.1039/P19760001190

Reference yield:

phenylacetyl chloride (103-80-0) → 4'-bromo-α-(phenylmethyl)(1,1'-biphenyl)-4-methanol (60313-17-9)

Guidance literature:

Multi-step reaction with 2 steps

1: AlCl₃

2: NaBH₄

With sodium tetrahydroborate; aluminium trichloride;

DOI:10.1039/P19760001190

upstream raw materials:

1-[4'-bromo(1,1'-biphenyl)-4-yl]-2-phenylethan-1-one

4-bromo-1,1'-biphenyl

phenylacetyl chloride

Downstream raw materials:

4-bromo-4'-(1-bromo-2-phenylethyl)-1,1'-biphenyl

3-(4''-Bromobiphenyl-4'-yl)-1,2,3,4-tetrahydronaphthalen-1-one

{1-[4'-bromo(1,1'-biphenyl)-4-yl]-2-phenylethyl}malonic acid