Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-(2-propynyl)-

Base Information

Chemical Name:Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-(2-propynyl)-
CAS No.:51094-98-5
Molecular Formula:C13H14N6O4
Molecular Weight:318.2881
Hs Code.:
DSSTox Substance ID:DTXSID30199092
Nikkaji Number:J342.258E
Wikidata:Q76150533

Synonyms:BRN 0584575;Adenosine-5'-(N-(2-propynyl))carboxamide;Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-(2-propynyl)-;1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-(2-propynyl)ribofuranuronamide;51094-98-5;(2~{S},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)-~{N}-prop-2-ynyl-oxolane-2-carboxamide;DTXSID30199092;C13H14N6O4;LS-143782;1-(6-Amino-9H-purin-9-yl)-N-(2-propynyl)-1-deoxy-beta-D-ribofuranuronamide;DKW

Suppliers and Price of Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-(2-propynyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-(2-propynyl)-

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.76g/cm³
XLogP3:-0.9
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:3
Exact Mass:318.10765295
Heavy Atom Count:23
Complexity:510

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C#CCNC(=O)C1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O
Isomeric SMILES:C#CCNC(=O)[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O

Technology Process of Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-(2-propynyl)-

There total 4 articles about Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-(2-propynyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 19234-66-3
2',3'-isopropylideneadenosine-5'-carboxylic acid

: 2450-71-7
Propargylamine

: 51094-98-5
1-(6-amino-purin-9-yl)-β-D-1-deoxy-ribofuranuronic acid prop-2-ynylamide

Guidance literature:: 2',3'-isopropylideneadenosine-5'-carboxylic acid; Propargylamine; With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 3h;

With trifluoroacetic acid; In water; at 0 ℃; for 3h;

Reference yield:

: (3aS,4S,6R,6aR)-6-(6-Amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid prop-2-ynylamide

: 51094-98-5
1-(6-amino-purin-9-yl)-β-D-1-deoxy-ribofuranuronic acid prop-2-ynylamide

Guidance literature:: With formic acid; at 60 - 70 ℃; for 2h;
DOI:10.1021/jm00177a021

Reference yield:

: 39491-49-1
2',3'-O-isopropylideneadenosine-5'-carbonyl chloride

: 51094-98-5
1-(6-amino-purin-9-yl)-β-D-1-deoxy-ribofuranuronic acid prop-2-ynylamide

Guidance literature:: Multi-step reaction with 2 steps

1: diethyl ether / 2 h / -60 - -40 °C

2: 50percent aq. HCOOH / 2 h / 60 - 70 °C

With formic acid; In diethyl ether;
DOI:10.1021/jm00177a021