N-Succinyl-alanyl-methionyl-S-benzylcysteine-4-nitroanilide

Base Information

Chemical Name:N-Succinyl-alanyl-methionyl-S-benzylcysteine-4-nitroanilide
CAS No.:117823-37-7
Molecular Formula:C₂₈H₃₅N₅O₈S₂
Molecular Weight:633.747
Hs Code.:
DSSTox Substance ID:DTXSID20151922
Wikidata:Q83018466
Mol file:117823-37-7.mol

Synonyms:N-succinyl-alanyl-methionyl-S-benzylcysteine-4-nitroanilide;SAMBN

Suppliers and Price of N-Succinyl-alanyl-methionyl-S-benzylcysteine-4-nitroanilide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N-Succinyl-alanyl-methionyl-S-benzylcysteine-4-nitroanilide

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:991.5°C at 760 mmHg
Flash Point:553.4°C
PSA：260.59000
Density:1.355g/cm³
LogP:5.67600
XLogP3:2.6
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:17
Exact Mass:633.19270544
Heavy Atom Count:43
Complexity:952

Purity/Quality:: 99% ，98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)NC(CCSC)C(=O)NC(=O)C(CSCC1=CC=CC=C1)NC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)CCC(=O)O
Isomeric SMILES:C[C@@H](C(=O)N[C@@H](CCSC)C(=O)NC(=O)[C@H](CSCC1=CC=CC=C1)NC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)CCC(=O)O

Technology Process of N-Succinyl-alanyl-methionyl-S-benzylcysteine-4-nitroanilide

There total 3 articles about N-Succinyl-alanyl-methionyl-S-benzylcysteine-4-nitroanilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 108-30-5
succinic acid anhydride

: (S)-2-((S)-2-Amino-propionylamino)-N-[(R)-2-benzylsulfanyl-1-(4-nitro-phenylcarbamoyl)-ethyl]-4-methylsulfanyl-butyramide

: 117823-37-7
3-carboxypropionylalanyl-methionyl-S-benzylcysteine p-nitroanilide

Guidance literature:: In N,N-dimethyl-formamide; at 80 ℃; for 2h;

Reference yield:

: 117823-40-2
tert-butyloxycarbonylalanyl-methionine

: 117823-37-7
3-carboxypropionylalanyl-methionyl-S-benzylcysteine p-nitroanilide

Guidance literature:: Multi-step reaction with 3 steps

1: 82 percent / DCC / CH₂Cl₂ / 12 h / 3 °C

2: HCl / acetic acid / 1 h / Ambient temperature

3: 51 percent / dimethylformamide / 2 h / 80 °C

With hydrogenchloride; dicyclohexyl-carbodiimide; In dichloromethane; acetic acid; N,N-dimethyl-formamide;

Reference yield:

: 117823-39-9
((S)-1-{(S)-1-[(R)-2-Benzylsulfanyl-1-(4-nitro-phenylcarbamoyl)-ethylcarbamoyl]-3-methylsulfanyl-propylcarbamoyl}-ethyl)-carbamic acid tert-butyl ester

: 117823-37-7
3-carboxypropionylalanyl-methionyl-S-benzylcysteine p-nitroanilide

Guidance literature:: Multi-step reaction with 2 steps

1: HCl / acetic acid / 1 h / Ambient temperature

2: 51 percent / dimethylformamide / 2 h / 80 °C

With hydrogenchloride; In acetic acid; N,N-dimethyl-formamide;