1-Isopropyl-4-(4-hydroxyphenyl)piperazine

Base Information

Chemical Name:1-Isopropyl-4-(4-hydroxyphenyl)piperazine
CAS No.:67914-97-0
Molecular Formula:C13H20 N2 O
Molecular Weight:220.315
Hs Code.:2933599090
European Community (EC) Number:267-750-0
DSSTox Substance ID:DTXSID70867400
Nikkaji Number:J287.744I
Wikidata:Q27203037
ChEMBL ID:CHEMBL1392389

Synonyms:67914-97-0;4-(4-isopropylpiperazin-1-yl)phenol;1-ISOPROPYL-4-(4-HYDROXYPHENYL)PIPERAZINE;4-(4-Isopropyl-piperazin-1-yl)-phenol;4-(4-propan-2-ylpiperazin-1-yl)phenol;EINECS 267-750-0;4-(4-isopropyl-1-piperazinyl)phenol;p-(4-Isopropyl-1-piperazinyl)phenol;4-[4-(propan-2-yl)piperazin-1-yl]phenol;P-[4-isopropyl-1-piperazinyl]phenol;Oprea1_105016;AN-907/14236005;MLS000698522;SCHEMBL3146325;CHEMBL1392389;DTXSID70867400;CHEBI:116817;HMS2549J12;MFCD02071478;AKOS015968317;4-[4-(1-Methylethyl)piperazino]phenol;4-(4-propan-2-yl-1-piperazinyl)phenol;NCGC00247233-01;AS-37937;SMR000231667;CS-0171963;FT-0641153;A835936;Q27203037;Z104658148;4-(4-ISOPROPYL-PIPERAZIN-1-YL)-PHENOL

Suppliers and Price of 1-Isopropyl-4-(4-hydroxyphenyl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-ISOPROPYL-4-(4-HYDROXYPHENYL)PIPERAZINE 95.00%
1G
$ 313.95

Alichem
4-(4-Isopropyl-piperazin-1-yl)-phenol
10g
$ 643.50

AK Scientific
1-Isopropyl-4-(4-hydroxyphenyl)piperazine
10g
$ 952.00

AK Scientific
1-Isopropyl-4-(4-hydroxyphenyl)piperazine
5g
$ 659.00

AHH
1-Isopropyl-4-(4-hydroxyphenyl)piperazine 98%
25g
$ 488.00

Total 45 raw suppliers

Chemical Property of 1-Isopropyl-4-(4-hydroxyphenyl)piperazine

Chemical Property:

Vapor Pressure:7.84E-06mmHg at 25°C
Melting Point:274.4 °C(Solv: 1-butanol (71-36-3))
Boiling Point:364.8°Cat760mmHg
PKA:12.18±0.30(Predicted)
Flash Point:181.1°C
PSA：26.71000
Density:1.083g/cm³
LogP:1.92550
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:220.157563266
Heavy Atom Count:16
Complexity:204

Purity/Quality:

99% ^*data from raw suppliers

1-ISOPROPYL-4-(4-HYDROXYPHENYL)PIPERAZINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)N1CCN(CC1)C2=CC=C(C=C2)O

Technology Process of 1-Isopropyl-4-(4-hydroxyphenyl)piperazine

There total 3 articles about 1-Isopropyl-4-(4-hydroxyphenyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 84499-46-7
4-(4-methoxyphenyl)-1-(1-methylethyl)piperazine

: 67914-97-0
4-(4-hydroxyphenyl)-1-(1-methylethyl)piperazine

Guidance literature:: With hydrogen bromide; Heating;
DOI:10.1021/jm00358a032

Reference yield: 83.0%

: 56621-48-8
1-(4-hydroxyphenyl)piperazine

: 67-64-1
acetone

: 67914-97-0
4-(4-hydroxyphenyl)-1-(1-methylethyl)piperazine

Guidance literature:: 1-(4-hydroxyphenyl)piperazine; acetone; With acetic acid; In methanol; at 60 ℃; for 0.5h;

With sodium cyanoborohydride; In methanol; at 60 ℃; for 16h;

With hydrogenchloride; water; In methanol;

Reference yield:

: 38869-47-5,70849-64-8
4-(p-methoxyphenyl)piperazine dihydrochloride

: 67914-97-0
4-(4-hydroxyphenyl)-1-(1-methylethyl)piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: H₂, NaOAc / 10percent Pd/C / methanol

2: 85 percent / 48percent HBr / Heating

With hydrogen bromide; hydrogen; sodium acetate; palladium on activated charcoal; In methanol;
DOI:10.1021/jm00358a032