Trans-2-(4-bromophenyl)cyclopropanecarboxylic acid

Base Information

Chemical Name:Trans-2-(4-bromophenyl)cyclopropanecarboxylic acid
CAS No.:6142-65-0
Molecular Formula:C₁₀H₉BrO₂
Molecular Weight:241.084
Hs Code.:
European Community (EC) Number:852-794-0

Synonyms:Trans-2-(4-bromophenyl)cyclopropanecarboxylic acid;6142-65-0;(1R,2R)-2-(4-bromophenyl)Cyclopropanecarboxylic acid;31501-85-6;(1R,2R)-2-(4-bromophenyl)cyclopropane-1-carboxylic acid;MFCD17215399;SCHEMBL455246;Cyclopropanecarboxylic acid, 2-(4-bromophenyl)-, (1R,2R);DPBUJVBXRABXRH-DTWKUNHWSA-N;MFCD29055398;AKOS015969635;BS-41770;CS-0037163;CS-0197883;EN300-250827;EN300-705387;W12440;W19711;A1-02943;(trans)-2-(4-bromophenyl) cyclopropanecarboxylic acid;(trans)-2-(4-bromophenyl)cyclopropanecarboxylic acid;2-(trans)-(4-bromophenyl)cyclopropanecarboxylic acid;trans 2-(4-Bromo-phenyl)-cyclopropanecarboxylic acid;(1R,2R)-2-(4-Bromo-phenyl)-cyclopropanecarboxylic acid;(+/-)-trans-2-(4-bromophenyl)cyclopropane-1-carboxylic acid;rac-(1R,2R)-2-(4-bromophenyl)cyclopropane-1-carboxylic acid;trans-(+/-)-2-(4-bromo-phenyl)-cyclopropanecarboxylic acid

Suppliers and Price of Trans-2-(4-bromophenyl)cyclopropanecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 5 raw suppliers

Chemical Property of Trans-2-(4-bromophenyl)cyclopropanecarboxylic acid

Chemical Property:

Vapor Pressure:5.95E-06mmHg at 25°C
Boiling Point:364.5°Cat760mmHg
Flash Point:174.2°C
Density:1.652g/cm³
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:239.97859
Heavy Atom Count:13
Complexity:209

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C1C(=O)O)C2=CC=C(C=C2)Br
Isomeric SMILES:C1[C@H]([C@@H]1C(=O)O)C2=CC=C(C=C2)Br

Technology Process of Trans-2-(4-bromophenyl)cyclopropanecarboxylic acid

There total 13 articles about Trans-2-(4-bromophenyl)cyclopropanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 53582-00-6,70461-61-9,91843-55-9
ethyl trans-2-(p-bromophenyl)-1-cyclopropanecarboxylate

: 6142-65-0,31501-85-6,77255-26-6,2137065-16-6
trans-(1S,2S)/(1R,2R)-2-(4-bromophenyl)cyclopropanecarboxylic acid

Guidance literature:: ethyl trans-2-(p-bromophenyl)-1-cyclopropanecarboxylate; With sodium hydroxide; In ethanol; at 20 ℃; Inert atmosphere;

With hydrogenchloride; In water; at 0 ℃; Inert atmosphere;
DOI:10.1039/c5ob02577j

Reference yield: 93.0%

: 134198-10-0
racemic 2-(4-bromo-phenyl)-trans-cyclopropanecarboxylic acid N-methoxy-N-methyl-amide

: 6142-65-0,31501-85-6,77255-26-6,2137065-16-6
trans-(1S,2S)/(1R,2R)-2-(4-bromophenyl)cyclopropanecarboxylic acid

Guidance literature:: With potassium tert-butylate; In diethyl ether; water;
DOI:10.1016/S0040-4039(00)79644-4

Reference yield:

: 24393-53-1,136265-11-7,15795-20-7
ethyl (E)-3-(4-bromophenyl)-2-propenoate

: 6142-65-0,31501-85-6,77255-26-6,2137065-16-6
trans-(1S,2S)/(1R,2R)-2-(4-bromophenyl)cyclopropanecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / dimethyl sulfoxide / 1 h / 20 °C

1.2: 0.5 h / 20 °C

2.1: sodium hydroxide / methanol / 2 h / 20 °C

With sodium hydride; sodium hydroxide; In methanol; dimethyl sulfoxide;