Ethyl 2-chloro-3-[4-(2-methyl-2-phenylpropoxy)phenyl]propanoate

Base Information

Chemical Name:Ethyl 2-chloro-3-[4-(2-methyl-2-phenylpropoxy)phenyl]propanoate
CAS No.:62516-91-0
Molecular Formula:C₂₁H₂₅ClO₃
Molecular Weight:360.881
Hs Code.:
DSSTox Substance ID:DTXSID80978112
Nikkaji Number:J40.896D
Wikidata:Q27154966
Mol file:62516-91-0.mol

Synonyms:AL 294;AL-294;ethyl 2-chloro-3-(4-(2-methyl-2-phenylpropyloxy)phenyl)propionate

Suppliers and Price of Ethyl 2-chloro-3-[4-(2-methyl-2-phenylpropoxy)phenyl]propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Ethyl 2-chloro-3-[4-(2-methyl-2-phenylpropoxy)phenyl]propanoate

Chemical Property:

Vapor Pressure:3.94E-09mmHg at 25°C
Boiling Point:473.4°Cat760mmHg
Flash Point:161.9°C
PSA：35.53000
Density:1.12g/cm³
LogP:4.75620
XLogP3:5.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:9
Exact Mass:360.1492223
Heavy Atom Count:25
Complexity:396

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(CC1=CC=C(C=C1)OCC(C)(C)C2=CC=CC=C2)Cl

Technology Process of Ethyl 2-chloro-3-[4-(2-methyl-2-phenylpropoxy)phenyl]propanoate

There total 13 articles about Ethyl 2-chloro-3-[4-(2-methyl-2-phenylpropoxy)phenyl]propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 62517-30-0
4-(2-methyl-2-phenylpropyloxy)aniline

: 1317-39-1,146060-06-2
copper(I) oxide

: 140-88-5,9003-32-1
ethyl acrylate

: 62516-91-0,74401-63-1
ethyl 2-chloro-3-[4-(2,2-dimethyl-2-phenylethyloxy)phenyl]propionate

Guidance literature:: With hydrogenchloride; sodium nitrite; In water; acetone;

Reference yield:

: 62517-29-7
4-(2-methyl-2-phenylpropyloxy)nitrobenzene

: 62516-91-0,74401-63-1
ethyl 2-chloro-3-[4-(2,2-dimethyl-2-phenylethyloxy)phenyl]propionate

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / 10percent Pd/C / benzene; ethanol / 760 Torr / Ambient temperature

2: 1.) 33percent NaNO₂/H₂O, conc. HCl, ethyl acrylate, 2.) Cu₂O / 1.) acetone, ice cooling, 2.) 40 deg C, 2 h

With copper(I) oxide; hydrogenchloride; water; hydrogen; ethyl acrylate; sodium nitrite; palladium on activated charcoal; In ethanol; benzene;

Reference yield:

: 2173-69-5
2-methyl-2-phenyl-propan-1-ol

: 62516-91-0,74401-63-1
ethyl 2-chloro-3-[4-(2,2-dimethyl-2-phenylethyloxy)phenyl]propionate

Guidance literature:: Multi-step reaction with 3 steps

1: 72 percent / NaH / dimethylsulfoxide / 3 h / 60 °C

2: H₂ / 10percent Pd/C / benzene; ethanol / 760 Torr / Ambient temperature

3: 1.) 33percent NaNO₂/H₂O, conc. HCl, ethyl acrylate, 2.) Cu₂O / 1.) acetone, ice cooling, 2.) 40 deg C, 2 h

With copper(I) oxide; hydrogenchloride; water; hydrogen; sodium hydride; ethyl acrylate; sodium nitrite; palladium on activated charcoal; In ethanol; dimethyl sulfoxide; benzene;