beta-Anilinochalcone

Base Information

• Chemical Name: beta-Anilinochalcone
• CAS No.: 63255-41-4
• Molecular Formula: C21H17NO
• Molecular Weight: 299.372
• NSC Number: 167326,167267
• Nikkaji Number: J472.300G
• Mol file: 63255-41-4.mol

Synonyms:beta-Anilinochalcone;NSC167267;20964-94-7;63255-41-4;SCHEMBL3080209;NSC167326;NSC-167267;NSC-167326

Chemical Property of beta-Anilinochalcone

Chemical Property:

• Boiling Point: 465.1°Cat760mmHg
• Flash Point: 160.4°C
• Density: 1.164g/cm³
• XLogP3: 5.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 299.131014166
• Heavy Atom Count: 23
• Complexity: 396

Purity/Quality:

90%,98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=CC(=O)C2=CC=CC=C2)NC3=CC=CC=C3
• Isomeric SMILES: C1=CC=C(C=C1)/C(=C\C(=O)C2=CC=CC=C2)/NC3=CC=CC=C3

Technology Process of beta-Anilinochalcone

There total 29 articles about beta-Anilinochalcone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

aniline (62-53-3) + 1,3-diphenyl-2-propynone (7338-94-5) → (Z)-1,3-diphenyl-3-(phenylamino)prop-2-en-1-one (63255-41-4)

Guidance literature:

at 80 ℃; for 1h;

DOI:10.1080/00397910801914343

Reference yield: 98.0%

(Z)-3-amino-1,3-diphenylprop-2-en-1-one (98815-39-5) + phenylboronic acid (98-80-6) → (Z)-1,3-diphenyl-3-(phenylamino)prop-2-en-1-one (63255-41-4)

Guidance literature:

With copper diacetate; triethylamine; In 1,2-dichloro-ethane; at 50 ℃; for 24h; Reagent/catalyst; Temperature; Catalytic behavior;

DOI:10.1016/j.tetlet.2018.10.030

Reference yield: 97.0%

C30H30N2Si → (Z)-1,3-diphenyl-3-(phenylamino)prop-2-en-1-one (63255-41-4)

Guidance literature:

With water; In ethanol; for 1.5h; Heating;

DOI:10.1002/ejoc.200700742

upstream raw materials:

1,3-diphenylpropanedione

aniline

(Z)-3-hydroxy-1,3-diphenyl-2-propen-1-one

1,3-diphenyl-2-propynone

Downstream raw materials:

[2,3-⁽¹³⁾C₂]-4-benzoyl-1,5-diphenyl-1H-pyrrol-2,3-dione

5-acetyl-3-benzoyl-1,4-dihydro-1, 2-diphenyl-6-methylpyridine

phenyl (2-phenyl-1H-indol-3-yl)methanone

5-benzoyl-1,6-diphenyl-3,4-dihydropyridin-2(1H)-one