phenyl (2-phenyl-1H-indol-3-yl)methanone

Base Information

• Chemical Name: phenyl (2-phenyl-1H-indol-3-yl)methanone
• CAS No.: 26862-65-7
• Molecular Formula: C₂₁H₁₅NO
• Molecular Weight: 297.356
• Mol file: 26862-65-7.mol

Synonyms:phenyl (2-phenyl-1H-indol-3-yl)methanone

Chemical Property of phenyl (2-phenyl-1H-indol-3-yl)methanone

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of phenyl (2-phenyl-1H-indol-3-yl)methanone

There total 45 articles about phenyl (2-phenyl-1H-indol-3-yl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

(Z)-1,3-diphenyl-3-(phenylamino)prop-2-en-1-one (63255-41-4) → phenyl (2-phenyl-1H-indol-3-yl)methanone (26862-65-7)

Guidance literature:

With copper(l) iodide; iodine; caesium carbonate; In 1,4-dioxane; for 5h; Reflux; Inert atmosphere;

DOI:10.1021/acs.joc.6b01960

Reference yield: 92.0%

(Z)-3-(2-iodophenylamino)-1,3-diphenylprop-2-en-1-one (75121-05-0) → phenyl (2-phenyl-1H-indol-3-yl)methanone (26862-65-7)

Guidance literature:

With copper(l) iodide; 1,10-Phenanthroline; potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 2.5h;

DOI:10.1055/s-0029-1216742

Reference yield: 92.0%

2-phenyl-indole (948-65-2) + benzoyl chloride (98-88-4) → phenyl (2-phenyl-1H-indol-3-yl)methanone (26862-65-7)

Guidance literature:

2-phenyl-indole; With diethylaluminium chloride; In hexane; dichloromethane; at 0 ℃; for 0.5h; Inert atmosphere;

benzoyl chloride; In hexane; dichloromethane; at 0 ℃; for 3.5h; Reagent/catalyst; Inert atmosphere;

DOI:10.1021/jo502463d

upstream raw materials:

2-(benzenesulfonyl)ethynylbenzene

(Z)-N-benzylideneaniline oxide

(E)-3-(2-Bromo-phenylamino)-1,3-diphenyl-propenone

3-(2-Iodophenyl)amino-1,3-diphenyl-2-propene-1-one

Downstream raw materials:

2-phenyl-indole

2-<<(4-methylphenyl)sulfonyl>oxy>ethyl benzoate