3-(4-chlorophenyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one

Base Information

Chemical Name:3-(4-chlorophenyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one
CAS No.:23429-91-6
Molecular Formula:C13H9 Cl N2 O S
Molecular Weight:276.746
Hs Code.:
Mol file:23429-91-6.mol

Synonyms:5H-Thiazolo[3,2-a]pyrimidin-5-one,3-(p-chlorophenyl)-7-methyl- (8CI); NSC 260553

Suppliers and Price of 3-(4-chlorophenyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of 3-(4-chlorophenyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one

Chemical Property:

Vapor Pressure:1.1E-07mmHg at 25°C
Boiling Point:432.5°C at 760 mmHg
Flash Point:215.4°C
Density:1.44g/cm³

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-(4-chlorophenyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one

There total 7 articles about 3-(4-chlorophenyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.91%

: 119730-10-8
2-((2-(4-chlorophenyl)-2-oxoethyl)thio)-6-methylpyrimidin-4(3H)-one

: 23429-91-6
3-(4-chlorophenyl)-7-methyl-5H-thiazolo<3,2-a>pyrimidin-5-one

Guidance literature:: With sulfuric acid; at 20 ℃; for 72h;
DOI:10.1007/s00044-015-1481-y

Reference yield: 12.0%

: 2103-99-3
4-(4-chlorophenyl)-2-thiazolamine

: 141-97-9
ethyl acetoacetate

: 23429-91-6
3-(4-chlorophenyl)-7-methyl-5H-thiazolo<3,2-a>pyrimidin-5-one

Guidance literature:: With trichlorophosphate; at 140 ℃; for 4h; Cooling with ice;

Reference yield:

: 99-91-2
para-chloroacetophenone

: 23429-91-6
3-(4-chlorophenyl)-7-methyl-5H-thiazolo<3,2-a>pyrimidin-5-one

Guidance literature:: Multi-step reaction with 2 steps

1: iodine / ethanol / 4 h / 70 °C

2: trichlorophosphate / 4 h / 140 °C / Cooling with ice

With iodine; trichlorophosphate; In ethanol;