(1R)-1-(4-Methoxyphenyl)-2-(methylamino)ethanol

Base Information

Chemical Name:(1R)-1-(4-Methoxyphenyl)-2-(methylamino)ethanol
CAS No.:57286-93-8
Molecular Formula:C10H15NO2
Molecular Weight:181.235
Hs Code.:

Synonyms:

Suppliers and Price of (1R)-1-(4-Methoxyphenyl)-2-(methylamino)ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of (1R)-1-(4-Methoxyphenyl)-2-(methylamino)ethanol

Chemical Property:

Boiling Point:315.4±32.0 °C(Predicted)
PKA:14.09±0.20(Predicted)
Density:1.067±0.06 g/cm3(Predicted)

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description This alkaloid, isolated from Dolicothele longimamma, differs from the accompanying bases in not having an isoquinoline structure. Instead, it belongs to the phenethylamine class of alkaloids. It is extracted from the EtOH fraction as the crystalline hydrochloride which forms colourless needles with m.p. 144- 6°C. This salt is optically active with a specific rotation of [α]25D - 76° and gives an ultraviolet spectrum in EtOH having absorption maxima at 225, 274 and 281 nm. The free base, prepared from the hydrochloride by standard chemical methods cannot be obtained in a crystalline form.

Technology Process of (1R)-1-(4-Methoxyphenyl)-2-(methylamino)ethanol

There total 8 articles about (1R)-1-(4-Methoxyphenyl)-2-(methylamino)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 117712-19-3
1-(4-methoxy-phenyl)-2-methylamino-ethanone

: 57286-93-8
(R)-(-)-α-<(methylamino)methyl>-4-methoxybenzenemethanol

Guidance literature:: With C₃₀H₂₉N₂OP; iron(II) acetate; In tetrahydrofuran; at 25 ℃; for 1h; Inert atmosphere;

Reference yield: 82.0%

: 131043-85-1
(4R,5R)-5-(4-Methoxy-phenyl)-4-(toluene-4-sulfonyl)-4,5-dihydro-oxazole

: 57286-93-8
(R)-(-)-α-<(methylamino)methyl>-4-methoxybenzenemethanol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; Ambient temperature;
DOI:10.1021/jo00311a007

Reference yield:

: 123-11-5
4-methoxy-benzaldehyde

: 57286-93-8
(R)-(-)-α-<(methylamino)methyl>-4-methoxybenzenemethanol

Guidance literature:: Multi-step reaction with 2 steps

1: silver triflate-chiral ligand 1b / CH₂Cl₂ / 2 h / 25 °C

2: 82 percent / LiAlH₄ / tetrahydrofuran / Ambient temperature

With lithium aluminium tetrahydride; silver triflate-chiral ligand 1b; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo00311a007