1-Benzoyl-2-benzylhydrazine

Base Information

• Chemical Name: 1-Benzoyl-2-benzylhydrazine
• CAS No.: 1215-52-7
• Molecular Formula: C14H14 N2 O
• Molecular Weight: 226.278
• Hs Code.: 2928000090
• Mol file: 1215-52-7.mol

Synonyms:Benzoicacid, 2-benzylhydrazide (6CI,7CI,8CI); NSC 50990; N'-Benzylbenzohydrazide

Chemical Property of 1-Benzoyl-2-benzylhydrazine

Chemical Property:

• Boiling Point: 350.9°Cat760mmHg
• Flash Point: 133.8°C
• PSA: 41.13000
• Density: 1.135g/cm³
• LogP: 2.90300

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Benzoyl-2-benzylhydrazine

There total 21 articles about 1-Benzoyl-2-benzylhydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

benzoic acid hydrazide (613-94-5) + benzyl alcohol (100-51-6,185532-71-2) → N-benzoyl-N'-benzylhydrazine (1215-52-7)

Guidance literature:

With nickel(II) triflate; 1,3-bis(dicyclohexylphosphine)propane; In tert-Amyl alcohol; at 120 ℃; for 24h; Inert atmosphere; Glovebox; Schlenk technique; Molecular sieve;

DOI:10.1002/anie.201708949

Reference yield: 95.0%

N'-benzoylbenzohydrazide (787-84-8) → N-benzoyl-N'-benzylhydrazine (1215-52-7)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol;

Reference yield: 85.0%

S-methyl O-benzyl dithiocarbonate (28925-45-3) + benzoic acid hydrazide (613-94-5) → N-benzoyl-N'-benzylhydrazine (1215-52-7)

Guidance literature:

With acetic acid; In ethanol; for 1h; Solvent; Reagent/catalyst; Catalytic behavior; Reflux; Green chemistry;

DOI:10.1080/00397911.2021.1933037

upstream raw materials:

benzoylhydrazone of benzaldehyde

N'-benzoylbenzohydrazide

benzyl chloride

benzoic acid hydrazide

Downstream raw materials:

benzoylhydrazone of benzaldehyde

1-benzyl-3-phenyl-1H-1,2,4-triazol-5(4H)-one

C₂₉H₂₈N₂O

C₂₉H₂₆N₂O

Refernces

• 1、 Sukrutha, Kodipura P.,Swaroop, Toreshettahally R.,Preetham, Ramesh,Lokanath, Neratur K.,Rangappa, Kanchugarakoppal S.,Sadashiva, Maralinganadoddi P.. "A convenient way for alkylation of amines using xanthate esters". . p. 2316 - 2323. Retrieved 2021/06/14.
• 2、 Yang, Peng,Zhang, Caili,Ma, Yu,Zhang, Caiyun,Li, Aijie,Tang, Bo,Zhou, Jianrong Steve. "Nickel-Catalyzed N-Alkylation of Acylhydrazines and Arylamines Using Alcohols and Enantioselective Examples". supporting information. p. 14702 - 14706. Retrieved 2017/10/20.