4-Ethyl-2-nitroaniline

Base Information

Chemical Name:4-Ethyl-2-nitroaniline
CAS No.:3663-35-2
Molecular Formula:C8H10 N2 O2
Molecular Weight:166.18
Hs Code.:2921420090
NSC Number:72325
DSSTox Substance ID:DTXSID30290997
Nikkaji Number:J2.685.828C
Wikidata:Q82028823
Mol file:3663-35-2.mol

Synonyms:4-ethyl-2-nitroaniline;3663-35-2;4-ETHYL-2-NITRO-ANILINE;2-nitro-4-ethylaniline;NSC 72325;4-ethyl-2-nitrobenzenamine;NSC72325;SCHEMBL1069671;DTXSID30290997;AMY28535;NSC-72325;AKOS005263755;BS-53323;CS-0168188;E82102

Suppliers and Price of 4-Ethyl-2-nitroaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
4-ETHYL-2-NITROANILINE AldrichCPR
1ea
$ 144.00

Matrix Scientific
4-Ethyl-2-nitroaniline
1g
$ 432.00

Total 8 raw suppliers

Chemical Property of 4-Ethyl-2-nitroaniline

Chemical Property:

Vapor Pressure:0.000479mmHg at 25°C
Melting Point:45-47 °C
Boiling Point:314°Cat760mmHg
PKA:0.45±0.10(Predicted)
Flash Point:143.7°C
PSA：71.84000
Density:1.218g/cm³
LogP:2.84380
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:166.074227566
Heavy Atom Count:12
Complexity:167

Purity/Quality:

97% ^*data from raw suppliers

4-ETHYL-2-NITROANILINE AldrichCPR ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=CC(=C(C=C1)N)[N+](=O)[O-]

Technology Process of 4-Ethyl-2-nitroaniline

There total 7 articles about 4-Ethyl-2-nitroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 3663-33-0
acetic acid-(4-ethyl-2-nitro-anilide)

: 3663-35-2
4-ethyl-2-nitroaniline

Guidance literature:: With potassium hydroxide; In ethanol; water; at 80 ℃; for 5h;
DOI:10.1021/acsmedchemlett.1c00613

Reference yield: 95.0%

: 589-16-2
4-aminoethylbenzene

: 3663-35-2
4-ethyl-2-nitroaniline

Guidance literature:: 4-aminoethylbenzene; With trifluoroacetic anhydride; In dichloromethane; at 0 ℃; for 0.25h; Reflux; Inert atmosphere; Glovebox; Schlenk technique;

With nitric acid; In dichloromethane; at 0 ℃; for 3h; Reflux; Inert atmosphere; Glovebox; Schlenk technique;
DOI:10.1002/ejic.201800511

Reference yield:

: 3663-34-1
N-(4-ethylphenyl)acetamide

: 3663-35-2
4-ethyl-2-nitroaniline

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; nitric acid

2: concentrated hydrochloric acid

With hydrogenchloride; nitric acid; acetic acid;